Platelet-derived growth factor induces Rad expression through Egr-1 in vascular smooth muscle cells.

Platelet-derived growth factor induces Rad expression through Egr-1 in vascular smooth muscle cells.

BACKGROUND: Ras associated with diabetes (Rad) inhibits vascular lesion formation by reducing the attachment and migration of vascular smooth muscle cells (VSMCs). However, the transcriptional regulation of Rad in VSMCs is unclear. METHODOLOGY AND PRINCIPAL FINDINGS: We found that Platelet-Derived G...

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Bibliographic Details
Main Authors: Yan Luo, Meiling Zhang, Ji Zhang, Jifeng Zhang, Chunlei Chen, Y Eugene Chen, Jing-Wei Xiong, Xiaojun Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3084842?pdf=render

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