High frequency of intron retention and clustered H3K4me3-marked nucleosomes in short first introns of human long non-coding RNAs

Abstract Background It is established that protein-coding exons are preferentially localized in nucleosomes. To examine whether the same is true for non-coding exons, we analysed nucleosome occupancy in and adjacent to internal exons in genes encoding long non-coding RNAs (lncRNAs) in human CD4+ T c...

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Detalles Bibliográficos
Autores principales: Pinki Dey, John S. Mattick
Formato: Artículo
Lenguaje:English
Publicado: BMC 2021-09-01
Colección:Epigenetics & Chromatin
Materias:
Acceso en línea:https://doi.org/10.1186/s13072-021-00419-2