TNF RECEPTOR 2 AND DISEASE: Autoimmunity and Regenerative Medicine

TNF RECEPTOR 2 AND DISEASE: Autoimmunity and Regenerative Medicine

The regulatory cytokine tumor necrosis factor (TNF) exerts its effects through two receptors: TNFR1 and TNFR2. Defects in TNFR2 signaling are evident in a variety of autoimmune diseases. One new treatment strategy for autoimmune disease is selective destruction of autoreactive T cells by administ...

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Bibliographic Details
Main Authors:	Denise Louise Faustman, Miriam eDavis
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2013-12-01
Series:	Frontiers in Immunology
Subjects:	Regeneration type 1 diabetes TNF autoimmune disease TNF Receptor 2
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00478/full

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