Experimental Substantiation of the Possibility to Use Finite Cell Line CHO-K1 for Determination of Specific Activity of Components of Chemical Cholera Vaccine

Experimental Substantiation of the Possibility to Use Finite Cell Line CHO-K1 for Determination of Specific Activity of Components of Chemical Cholera Vaccine

Objective was to experimentally substantiate the possibility to use the finite cell line CHO-K1 for measuring specific activity of cholera toxin and component of the vaccine choleragen-anatoxin in the process of chemical cholera vaccine manufacturing. Materials and methods. The studies involved the...

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Bibliographic Details
Main Authors: O. S. Durakova, O. V. Gromova, A. V. Gaeva, S. V. Generalov, L. F. Livanova, O. D. Klokova, O. A. Volokh
Format: Article
Language:Russian
Published: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2020-01-01
Series:Проблемы особо опасных инфекций
Subjects:
chemical cholera vaccine
cell culture cho-k1
cholera toxin
choleragen-anatoxin
Online Access:https://journal.microbe.ru/jour/article/view/1220

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