The key role of 99mTc-MIBI SPECT/CT in the diagnosis of parathyroid adenoma: a case report

The concomitant occurrence of primary hyperparathyroidism (PHPT) due to parathyroid adenoma and papillary thyroid carcinoma (PTC) is not common. The co-occurrence of parathyroid tumors and thyroid diseases can lead to misdiagnosis owing to mutual interference of imaging in the early period of diseas...

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Main Authors: Qing Li, Jiemin Pan, Quanyong Luo, Yan Wang, Yuqian Bao, Weiping Jia
Format: Article
Language:English
Published: Brazilian Society of Endocrinology and Metabolism
Series:Archives of Endocrinology and Metabolism
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972015000300265&lng=en&tlng=en
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author Qing Li
Jiemin Pan
Quanyong Luo
Yan Wang
Yuqian Bao
Weiping Jia
author_facet Qing Li
Jiemin Pan
Quanyong Luo
Yan Wang
Yuqian Bao
Weiping Jia
author_sort Qing Li
collection DOAJ
description The concomitant occurrence of primary hyperparathyroidism (PHPT) due to parathyroid adenoma and papillary thyroid carcinoma (PTC) is not common. The co-occurrence of parathyroid tumors and thyroid diseases can lead to misdiagnosis owing to mutual interference of imaging in the early period of disease. The most commonly used imaging techniques for the preoperative localization of parathyroid and thyroid adenomas are technetium-99m sestamibi (99mTc-MIBI) scintigraphy and ultrasonography of the neck. Recently, 99mTc-MIBI single-photon emission computed tomography associated with computed tomography scintigraphy (SPECT/CT) has been used to detect PHPT, and its diagnostic value is being evaluated. Herein, we report a patient with an unusual co-occurrence of parathyroid adenoma and multiple thyroid diseases, including papillary thyroid carcinoma, thyroid adenoma and lymphocytic thyroiditis, which were localized with 99mTc-MIBI SPECT/CT and confirmed surgically. We suggest that 99mTc-MIBI SPECT/CT can play an important role in the diagnosis of parathyroid and thyroid lesions. Arch Endocrinol Metab. 2015;59(3):265-9
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spelling doaj.art-4f40011898254702b21eb34e7180e8372022-12-21T19:05:46ZengBrazilian Society of Endocrinology and MetabolismArchives of Endocrinology and Metabolism2359-429259326526910.1590/2359-3997000000048S2359-39972015000300265The key role of 99mTc-MIBI SPECT/CT in the diagnosis of parathyroid adenoma: a case reportQing LiJiemin PanQuanyong LuoYan WangYuqian BaoWeiping JiaThe concomitant occurrence of primary hyperparathyroidism (PHPT) due to parathyroid adenoma and papillary thyroid carcinoma (PTC) is not common. The co-occurrence of parathyroid tumors and thyroid diseases can lead to misdiagnosis owing to mutual interference of imaging in the early period of disease. The most commonly used imaging techniques for the preoperative localization of parathyroid and thyroid adenomas are technetium-99m sestamibi (99mTc-MIBI) scintigraphy and ultrasonography of the neck. Recently, 99mTc-MIBI single-photon emission computed tomography associated with computed tomography scintigraphy (SPECT/CT) has been used to detect PHPT, and its diagnostic value is being evaluated. Herein, we report a patient with an unusual co-occurrence of parathyroid adenoma and multiple thyroid diseases, including papillary thyroid carcinoma, thyroid adenoma and lymphocytic thyroiditis, which were localized with 99mTc-MIBI SPECT/CT and confirmed surgically. We suggest that 99mTc-MIBI SPECT/CT can play an important role in the diagnosis of parathyroid and thyroid lesions. Arch Endocrinol Metab. 2015;59(3):265-9http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972015000300265&lng=en&tlng=en
spellingShingle Qing Li
Jiemin Pan
Quanyong Luo
Yan Wang
Yuqian Bao
Weiping Jia
The key role of 99mTc-MIBI SPECT/CT in the diagnosis of parathyroid adenoma: a case report
Archives of Endocrinology and Metabolism
title The key role of 99mTc-MIBI SPECT/CT in the diagnosis of parathyroid adenoma: a case report
title_full The key role of 99mTc-MIBI SPECT/CT in the diagnosis of parathyroid adenoma: a case report
title_fullStr The key role of 99mTc-MIBI SPECT/CT in the diagnosis of parathyroid adenoma: a case report
title_full_unstemmed The key role of 99mTc-MIBI SPECT/CT in the diagnosis of parathyroid adenoma: a case report
title_short The key role of 99mTc-MIBI SPECT/CT in the diagnosis of parathyroid adenoma: a case report
title_sort key role of 99mtc mibi spect ct in the diagnosis of parathyroid adenoma a case report
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972015000300265&lng=en&tlng=en
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