Rap1 Negatively Regulates the Hippo Pathway to Polarize Directional Protrusions in Collective Cell Migration
Summary: In collective cell migration, directional protrusions orient cells in response to external cues, which requires coordinated polarity among the migrating cohort. However, the molecular mechanism has not been well defined. Drosophila border cells (BCs) migrate collectively and invade via the...
Main Authors: | Yu-Chiuan Chang, Jhen-Wei Wu, Yi-Chi Hsieh, Tzu-Han Huang, Zih-Min Liao, Yi-Shan Huang, James A. Mondo, Denise Montell, Anna C.-C. Jang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-02-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221112471830144X |
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