H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs

H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs

Summary: Histone variant H2A.Z occupies the promoters of active and poised, bivalent genes in embryonic stem cells (ESCs) to regulate developmental programs, yet how it contributes to these contrasting states is poorly understood. Here, we investigate the function of H2A.Z.1 monoubiquitylation (H2A....

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Príomhchruthaitheoirí: Lauren E. Surface, Paul A. Fields, Vidya Subramanian, Russell Behmer, Namrata Udeshi, Sally E. Peach, Steven A. Carr, Jacob D. Jaffe, Laurie A. Boyer
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Elsevier 2016-02-01
Sraith:Cell Reports
Rochtain ar líne:http://www.sciencedirect.com/science/article/pii/S2211124715015569

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http://www.sciencedirect.com/science/article/pii/S2211124715015569

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