Impact of an 18F-FDG PET/CT Radiotracer Injection Infiltration on Patient Management—A Case Report
Major management decisions in patients with solid tumors and lymphomas are often based on 18F-fluorodeoxyglucose (18F-FDG) PET/CT. The misadministration of 18F-FDG outside the systemic circulation can have an adverse impact on this test's sensitivity (1) and is not uncommon (2–7). This report d...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-05-01
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| Series: | Frontiers in Medicine |
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| Online Access: | http://journal.frontiersin.org/article/10.3389/fmed.2018.00143/full |
| _version_ | 1818923651452370944 |
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| author | Jackson W. Kiser James R. Crowley David A. Wyatt Ronald K. Lattanze |
| author_facet | Jackson W. Kiser James R. Crowley David A. Wyatt Ronald K. Lattanze |
| author_sort | Jackson W. Kiser |
| collection | DOAJ |
| description | Major management decisions in patients with solid tumors and lymphomas are often based on 18F-fluorodeoxyglucose (18F-FDG) PET/CT. The misadministration of 18F-FDG outside the systemic circulation can have an adverse impact on this test's sensitivity (1) and is not uncommon (2–7). This report describes how an 18F-FDG misadministration led to a repeat PET/CT study, resulting in the visualization of distant metastases that changed the original treatment plan. The findings suggest that routine injection monitoring is indicated whenever sensitivity is critical, and support claims that infiltrations can confound interpretation of semi-quantitative PET outcome measures in patients who are followed longitudinally (2). |
| first_indexed | 2024-12-20T02:12:49Z |
| format | Article |
| id | doaj.art-4f483c3431e24f7e870c170592ce3e5f |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-12-20T02:12:49Z |
| publishDate | 2018-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-4f483c3431e24f7e870c170592ce3e5f2022-12-21T19:57:00ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2018-05-01510.3389/fmed.2018.00143347074Impact of an 18F-FDG PET/CT Radiotracer Injection Infiltration on Patient Management—A Case ReportJackson W. Kiser0James R. Crowley1David A. Wyatt2Ronald K. Lattanze3Carilion Clinic, Roanoke, VA, United StatesCarilion Clinic, Roanoke, VA, United StatesCarilion Clinic, Roanoke, VA, United StatesLucerno Dynamics, Cary, NC, United StatesMajor management decisions in patients with solid tumors and lymphomas are often based on 18F-fluorodeoxyglucose (18F-FDG) PET/CT. The misadministration of 18F-FDG outside the systemic circulation can have an adverse impact on this test's sensitivity (1) and is not uncommon (2–7). This report describes how an 18F-FDG misadministration led to a repeat PET/CT study, resulting in the visualization of distant metastases that changed the original treatment plan. The findings suggest that routine injection monitoring is indicated whenever sensitivity is critical, and support claims that infiltrations can confound interpretation of semi-quantitative PET outcome measures in patients who are followed longitudinally (2).http://journal.frontiersin.org/article/10.3389/fmed.2018.00143/fullPET-CTextravasation of diagnostic and therapeutic materialsSUVFDGtime activity curve |
| spellingShingle | Jackson W. Kiser James R. Crowley David A. Wyatt Ronald K. Lattanze Impact of an 18F-FDG PET/CT Radiotracer Injection Infiltration on Patient Management—A Case Report Frontiers in Medicine PET-CT extravasation of diagnostic and therapeutic materials SUV FDG time activity curve |
| title | Impact of an 18F-FDG PET/CT Radiotracer Injection Infiltration on Patient Management—A Case Report |
| title_full | Impact of an 18F-FDG PET/CT Radiotracer Injection Infiltration on Patient Management—A Case Report |
| title_fullStr | Impact of an 18F-FDG PET/CT Radiotracer Injection Infiltration on Patient Management—A Case Report |
| title_full_unstemmed | Impact of an 18F-FDG PET/CT Radiotracer Injection Infiltration on Patient Management—A Case Report |
| title_short | Impact of an 18F-FDG PET/CT Radiotracer Injection Infiltration on Patient Management—A Case Report |
| title_sort | impact of an 18f fdg pet ct radiotracer injection infiltration on patient management a case report |
| topic | PET-CT extravasation of diagnostic and therapeutic materials SUV FDG time activity curve |
| url | http://journal.frontiersin.org/article/10.3389/fmed.2018.00143/full |
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