Foster Kennedy syndrome secondary to a giant prolactinoma with a remarkable response to cabergoline
Pituitary adenomas are intracranial neoplasms, usually demonstrating a benign phenotype. We present the case of 21-year-old male with an 18-month history of reduced visual function (acuity and field) in the left eye. Based on neuroimaging and endocrine profile, a giant prolactinoma causing hypogonad...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Bioscientifica
2022-08-01
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| Series: | Endocrinology, Diabetes & Metabolism Case Reports |
| Online Access: | https://edm.bioscientifica.com/view/journals/edm/2022/1/EDM22-0261.xml |
| _version_ | 1817995418383941632 |
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| author | Usama Kanj Sam Sum Lee Milanka Wattegama Swarupsinh Chavda Niki Karavitaki Ruchika Batra |
| author_facet | Usama Kanj Sam Sum Lee Milanka Wattegama Swarupsinh Chavda Niki Karavitaki Ruchika Batra |
| author_sort | Usama Kanj |
| collection | DOAJ |
| description | Pituitary adenomas are intracranial neoplasms, usually demonstrating a benign phenotype. We present the case of 21-year-old male with an 18-month history of reduced visual function (acuity and field) in the left eye. Based on neuroimaging and endocrine profile, a giant prolactinoma causing hypogonadotropic hypogonadism was diagnosed and cabergoline was commenced. After a month of treatment, the tumour size reduced, and visual function improved to normal; however, he developed Foster Kennedy syndrome with a swollen right optic disc. After almost 1 year of follow-up, he regained full visual functioning. Two years since his diagnosis, his prolactin remains normal with no adverse effects or further visual complications. |
| first_indexed | 2024-04-14T02:06:46Z |
| format | Article |
| id | doaj.art-4f49c6bc91544387921e9062e1dae273 |
| institution | Directory Open Access Journal |
| issn | 2052-0573 |
| language | English |
| last_indexed | 2024-04-14T02:06:46Z |
| publishDate | 2022-08-01 |
| publisher | Bioscientifica |
| record_format | Article |
| series | Endocrinology, Diabetes & Metabolism Case Reports |
| spelling | doaj.art-4f49c6bc91544387921e9062e1dae2732022-12-22T02:18:39ZengBioscientificaEndocrinology, Diabetes & Metabolism Case Reports2052-05732022-08-01111510.1530/EDM-22-0261Foster Kennedy syndrome secondary to a giant prolactinoma with a remarkable response to cabergolineUsama Kanj0Sam Sum Lee1Milanka Wattegama2Swarupsinh Chavda3Niki Karavitaki4Ruchika Batra5Department of OphthalmologyDepartment of OphthalmologyDepartment of EndocrinologyDepartment of Neuroradiology, University Hospitals Birmingham NHS Trust, Birmingham, UKDepartment of Endocrinology; Institute of Metabolism and Systems Research, University of Bimingham, Birmingham, UK; Center for Endocrinology, Diabetes and Metabolism, Birmingham, UK Birmingham Neuro-Ophthalmology Unit, University Hospitals Birmingham NHS Trust, Birmingham, UKPituitary adenomas are intracranial neoplasms, usually demonstrating a benign phenotype. We present the case of 21-year-old male with an 18-month history of reduced visual function (acuity and field) in the left eye. Based on neuroimaging and endocrine profile, a giant prolactinoma causing hypogonadotropic hypogonadism was diagnosed and cabergoline was commenced. After a month of treatment, the tumour size reduced, and visual function improved to normal; however, he developed Foster Kennedy syndrome with a swollen right optic disc. After almost 1 year of follow-up, he regained full visual functioning. Two years since his diagnosis, his prolactin remains normal with no adverse effects or further visual complications.https://edm.bioscientifica.com/view/journals/edm/2022/1/EDM22-0261.xml |
| spellingShingle | Usama Kanj Sam Sum Lee Milanka Wattegama Swarupsinh Chavda Niki Karavitaki Ruchika Batra Foster Kennedy syndrome secondary to a giant prolactinoma with a remarkable response to cabergoline Endocrinology, Diabetes & Metabolism Case Reports |
| title | Foster Kennedy syndrome secondary to a giant prolactinoma with a remarkable response to cabergoline |
| title_full | Foster Kennedy syndrome secondary to a giant prolactinoma with a remarkable response to cabergoline |
| title_fullStr | Foster Kennedy syndrome secondary to a giant prolactinoma with a remarkable response to cabergoline |
| title_full_unstemmed | Foster Kennedy syndrome secondary to a giant prolactinoma with a remarkable response to cabergoline |
| title_short | Foster Kennedy syndrome secondary to a giant prolactinoma with a remarkable response to cabergoline |
| title_sort | foster kennedy syndrome secondary to a giant prolactinoma with a remarkable response to cabergoline |
| url | https://edm.bioscientifica.com/view/journals/edm/2022/1/EDM22-0261.xml |
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