Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase

Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase

GPIHBP1 is a glycosylphosphatidylinositol-anchored protein in the lymphocyte antigen 6 (Ly-6) family that recently was identified as a platform for the lipolytic processing of triglyceride-rich lipoproteins. GPIHBP1 binds both LPL and chylomicrons and is expressed on the luminal face of microvascula...

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Bibliographic Details
Main Authors: Anne P. Beigneux, Peter Gin, Brandon S.J. Davies, Michael M. Weinstein, André Bensadoun, Robert O. Ryan, Loren G. Fong, Stephen G. Young
Format: Article
Language:English
Published: Elsevier 2008-06-01
Series:Journal of Lipid Research
Subjects:
glycosylphosphatidylinositol-anchored HDL binding protein 1
knockout mice
chylomicronemia
hypertriglyceridemia
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520423752

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