Reconstruction of a polyclonal ADCC antibody repertoire from an HIV-1 non-transmitting mother

Reconstruction of a polyclonal ADCC antibody repertoire from an HIV-1 non-transmitting mother

Summary: Human natural history and vaccine studies support a protective role of antibody dependent cellular cytotoxicity (ADCC) activity against many infectious diseases. One setting where this has consistently been observed is in HIV-1 vertical transmission, where passively acquired ADCC activity i...

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Bibliographic Details
Main Authors: Zak A. Yaffe, Shilei Ding, Kevin Sung, Vrasha Chohan, Lorie Marchitto, Laura Doepker, Duncan Ralph, Ruth Nduati, Frederick A. Matsen, IV, Andrés Finzi, Julie Overbaugh
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:iScience
Subjects:
Immunology
Pediatrics
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223008398

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