EFFICACY OF COMBINATION TREATMENT WITH ANTI_IGE PLUS SPECIFIC IMMUNOTHERAPY IN PATIENTS WITH ATOPIC DISEASES
Allergen specific immunotherapy (ASIT) is a very effective technique in treatment of many allergic diseases. It greatly improves the quality of life. There's a risk of adverse system reactions at the time of ASIT. Treatment with anti Ige antibodies (omalizumab, xolair) allows decreasing the cir...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
"Paediatrician" Publishers LLC
2008-06-01
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| Series: | Вопросы современной педиатрии |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/1397 |
| _version_ | 1797697745296818176 |
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| author | N.I. Il'ina O.M. Kurbacheva K.S. Pavlova |
| author_facet | N.I. Il'ina O.M. Kurbacheva K.S. Pavlova |
| author_sort | N.I. Il'ina |
| collection | DOAJ |
| description | Allergen specific immunotherapy (ASIT) is a very effective technique in treatment of many allergic diseases. It greatly improves the quality of life. There's a risk of adverse system reactions at the time of ASIT. Treatment with anti Ige antibodies (omalizumab, xolair) allows decreasing the circulating Ige level and lessening an expression of high affinity fc_r1 receptors on the surface of basophiles and mast cells, inhibition of early and late phase of allergic inflammatory response. Combination of antibige therapy and ASIT can lead to decrease of risk of adverse system reactions.Key words: omalizumab, anti Ige antibodies, allergen specific immunotherapy. |
| first_indexed | 2024-03-12T03:44:29Z |
| format | Article |
| id | doaj.art-4f4cc9dff75c4dcfb5999e5f94a5af52 |
| institution | Directory Open Access Journal |
| issn | 1682-5527 1682-5535 |
| language | English |
| last_indexed | 2024-03-12T03:44:29Z |
| publishDate | 2008-06-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj.art-4f4cc9dff75c4dcfb5999e5f94a5af522023-09-03T12:58:19Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352008-06-017344511397EFFICACY OF COMBINATION TREATMENT WITH ANTI_IGE PLUS SPECIFIC IMMUNOTHERAPY IN PATIENTS WITH ATOPIC DISEASESN.I. Il'ina0O.M. Kurbacheva1K.S. Pavlova2Институт иммунологии, МоскваИнститут иммунологии, МоскваИнститут иммунологии, МоскваAllergen specific immunotherapy (ASIT) is a very effective technique in treatment of many allergic diseases. It greatly improves the quality of life. There's a risk of adverse system reactions at the time of ASIT. Treatment with anti Ige antibodies (omalizumab, xolair) allows decreasing the circulating Ige level and lessening an expression of high affinity fc_r1 receptors on the surface of basophiles and mast cells, inhibition of early and late phase of allergic inflammatory response. Combination of antibige therapy and ASIT can lead to decrease of risk of adverse system reactions.Key words: omalizumab, anti Ige antibodies, allergen specific immunotherapy.https://vsp.spr-journal.ru/jour/article/view/1397 |
| spellingShingle | N.I. Il'ina O.M. Kurbacheva K.S. Pavlova EFFICACY OF COMBINATION TREATMENT WITH ANTI_IGE PLUS SPECIFIC IMMUNOTHERAPY IN PATIENTS WITH ATOPIC DISEASES Вопросы современной педиатрии |
| title | EFFICACY OF COMBINATION TREATMENT WITH ANTI_IGE PLUS SPECIFIC IMMUNOTHERAPY IN PATIENTS WITH ATOPIC DISEASES |
| title_full | EFFICACY OF COMBINATION TREATMENT WITH ANTI_IGE PLUS SPECIFIC IMMUNOTHERAPY IN PATIENTS WITH ATOPIC DISEASES |
| title_fullStr | EFFICACY OF COMBINATION TREATMENT WITH ANTI_IGE PLUS SPECIFIC IMMUNOTHERAPY IN PATIENTS WITH ATOPIC DISEASES |
| title_full_unstemmed | EFFICACY OF COMBINATION TREATMENT WITH ANTI_IGE PLUS SPECIFIC IMMUNOTHERAPY IN PATIENTS WITH ATOPIC DISEASES |
| title_short | EFFICACY OF COMBINATION TREATMENT WITH ANTI_IGE PLUS SPECIFIC IMMUNOTHERAPY IN PATIENTS WITH ATOPIC DISEASES |
| title_sort | efficacy of combination treatment with anti ige plus specific immunotherapy in patients with atopic diseases |
| url | https://vsp.spr-journal.ru/jour/article/view/1397 |
| work_keys_str_mv | AT niilina efficacyofcombinationtreatmentwithantiigeplusspecificimmunotherapyinpatientswithatopicdiseases AT omkurbacheva efficacyofcombinationtreatmentwithantiigeplusspecificimmunotherapyinpatientswithatopicdiseases AT kspavlova efficacyofcombinationtreatmentwithantiigeplusspecificimmunotherapyinpatientswithatopicdiseases |