Mycoplasma hyorhinis infection promotes TNF-α signaling and SMAC mimetic-mediated apoptosis in human prostate cancer

Mycoplasma hyorhinis infection promotes TNF-α signaling and SMAC mimetic-mediated apoptosis in human prostate cancer

Growing evidence suggests an association between Mycoplasma infections and the development and progression of prostate cancer (PCa). In this study, we report that chronic and persistent M. hyorhinis infection induced robust TNF-α secretion from PCa cells. TNF-α secreted from M. hyorhinis-infected PC...

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Bibliographic Details
Main Authors: Jin Koo Kim, Insoon Chang, Younghun Jung, Zach Kaplan, Elliott E. Hill, Russell S. Taichman, Paul H. Krebsbach
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Heliyon
Subjects:
Mycoplasma hyorhinis
Prostate cancer
TNF-α
NF-κB
SMAC mimetic
AZD5582
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023078635

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