Prevalence of Depression and Related Factors among Patients with Chronic Disease during the COVID-19 Pandemic: A Systematic Review and Meta-Analysis

The management of chronic diseases in the midst of the COVID-19 pandemic is especially challenging, and reducing potential psychological harm is essential. This review aims to determine the prevalence of depression during the COVID-19 pandemic in patients with chronic disease, and to characterize th...

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Main Authors: Rubén A. García-Lara, Nora Suleiman-Martos, María J. Membrive-Jiménez, Victoria García-Morales, Miguel Quesada-Caballero, Isabel M. Guisado-Requena, José L. Gómez-Urquiza
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/12/12/3094
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author Rubén A. García-Lara
Nora Suleiman-Martos
María J. Membrive-Jiménez
Victoria García-Morales
Miguel Quesada-Caballero
Isabel M. Guisado-Requena
José L. Gómez-Urquiza
author_facet Rubén A. García-Lara
Nora Suleiman-Martos
María J. Membrive-Jiménez
Victoria García-Morales
Miguel Quesada-Caballero
Isabel M. Guisado-Requena
José L. Gómez-Urquiza
author_sort Rubén A. García-Lara
collection DOAJ
description The management of chronic diseases in the midst of the COVID-19 pandemic is especially challenging, and reducing potential psychological harm is essential. This review aims to determine the prevalence of depression during the COVID-19 pandemic in patients with chronic disease, and to characterize the impacts of related factors. A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The meta-analysis was performed using StatsDirect software. The review identified 33 articles with a total of 50,905 patients with chronic diseases. Four meta-analyses were performed to estimate the prevalence of depression. In diabetic patients, the prevalence ranged from 17% (95% CI = 7–31) (PHQ-9) to 33% (95% CI = 16–51) (PHQ-8); in obese patients, the prevalence was 48% (95% CI = 26–71); and in hypertensive patients, the prevalence was 18% (95% CI = 13–24). The factors significantly associated with depression were female sex, being single, deterioration in the clinical parameters of diabetes, a decrease in self-care behavior, reduced physical activity and sleep time and fear of contagion. The COVID-19 pandemic has significantly increased levels of depression among persons with chronic disease. Pandemics and other emergency events have a major impact on mental health, so early psychological interventions and health management policies are needed to reinforce chronic patients’ physical and mental health.
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spelling doaj.art-4f4e834b1f714deeab6ac2cb99c78db52023-11-24T14:18:32ZengMDPI AGDiagnostics2075-44182022-12-011212309410.3390/diagnostics12123094Prevalence of Depression and Related Factors among Patients with Chronic Disease during the COVID-19 Pandemic: A Systematic Review and Meta-AnalysisRubén A. García-Lara0Nora Suleiman-Martos1María J. Membrive-Jiménez2Victoria García-Morales3Miguel Quesada-Caballero4Isabel M. Guisado-Requena5José L. Gómez-Urquiza6UGC Orgiva, Granada-South Health Management Area, Andalusian Health Service, Calle La Madre s/n, Lanjarón, 18420 Granada, SpainNursing Department, Faculty of Health Sciences, University of Granada, Av. de la Ilustración, 60, 18016 Granada, SpainRed Cross Nursing Center, University of Sevilla, Av. la Cruz Roja, 41009 Sevilla, SpainDepartment of Biomedicine, Biotechnology and Public Health, Faculty of Medicine, University of Cadiz, Pl. Falla, 9, 11003 Cadiz, SpainUGC La Caleta Granada-Metropolitano, Andalusian Health Service, Av. del Sur, 11, 18014 Granada, SpainNursing Department, Faculty of Health Sciences, University of Castilla la Mancha, 02006 Albacete, SpainNursing Department, Faculty of Health Sciences, University of Granada, Cortadura del Valle s/n, 51001 Ceuta, SpainThe management of chronic diseases in the midst of the COVID-19 pandemic is especially challenging, and reducing potential psychological harm is essential. This review aims to determine the prevalence of depression during the COVID-19 pandemic in patients with chronic disease, and to characterize the impacts of related factors. A systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The meta-analysis was performed using StatsDirect software. The review identified 33 articles with a total of 50,905 patients with chronic diseases. Four meta-analyses were performed to estimate the prevalence of depression. In diabetic patients, the prevalence ranged from 17% (95% CI = 7–31) (PHQ-9) to 33% (95% CI = 16–51) (PHQ-8); in obese patients, the prevalence was 48% (95% CI = 26–71); and in hypertensive patients, the prevalence was 18% (95% CI = 13–24). The factors significantly associated with depression were female sex, being single, deterioration in the clinical parameters of diabetes, a decrease in self-care behavior, reduced physical activity and sleep time and fear of contagion. The COVID-19 pandemic has significantly increased levels of depression among persons with chronic disease. Pandemics and other emergency events have a major impact on mental health, so early psychological interventions and health management policies are needed to reinforce chronic patients’ physical and mental health.https://www.mdpi.com/2075-4418/12/12/3094COVID-19chronic diseasedepressionprevalencerelated factors
spellingShingle Rubén A. García-Lara
Nora Suleiman-Martos
María J. Membrive-Jiménez
Victoria García-Morales
Miguel Quesada-Caballero
Isabel M. Guisado-Requena
José L. Gómez-Urquiza
Prevalence of Depression and Related Factors among Patients with Chronic Disease during the COVID-19 Pandemic: A Systematic Review and Meta-Analysis
Diagnostics
COVID-19
chronic disease
depression
prevalence
related factors
title Prevalence of Depression and Related Factors among Patients with Chronic Disease during the COVID-19 Pandemic: A Systematic Review and Meta-Analysis
title_full Prevalence of Depression and Related Factors among Patients with Chronic Disease during the COVID-19 Pandemic: A Systematic Review and Meta-Analysis
title_fullStr Prevalence of Depression and Related Factors among Patients with Chronic Disease during the COVID-19 Pandemic: A Systematic Review and Meta-Analysis
title_full_unstemmed Prevalence of Depression and Related Factors among Patients with Chronic Disease during the COVID-19 Pandemic: A Systematic Review and Meta-Analysis
title_short Prevalence of Depression and Related Factors among Patients with Chronic Disease during the COVID-19 Pandemic: A Systematic Review and Meta-Analysis
title_sort prevalence of depression and related factors among patients with chronic disease during the covid 19 pandemic a systematic review and meta analysis
topic COVID-19
chronic disease
depression
prevalence
related factors
url https://www.mdpi.com/2075-4418/12/12/3094
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