Platelet desialylation correlates with efficacy of first-line therapies for immune thrombocytopenia

Platelet desialylation correlates with efficacy of first-line therapies for immune thrombocytopenia

Abstract Immune thrombocytopenia (ITP) is a common autoimmune bleeding disorder. Despite considerable investigation, the pathogenesis of ITP remains incompletely understood, and for many patients, effective therapy is still unavailable. Using murine models and in vitro studies of human blood samples...

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Bibliographic Details
Main Authors: Lili Tao, Qingshu Zeng, June Li, Miao Xu, Jiajia Wang, Ying Pan, Huiping Wang, Qianshan Tao, Yang Chen, Jun Peng, Ming Hou, Arend Jan Gerard Jansen, Heyu Ni, Zhimin Zhai
Format: Article
Language:English
Published: BMC 2017-02-01
Series:Journal of Hematology & Oncology
Subjects:
Platelet
Immune thrombocytopenia
Antibody
Desialylation
Steroid and IVIG therapy
Online Access:http://link.springer.com/article/10.1186/s13045-017-0413-3

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