Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes
The cellular composition of previous engineered heart tissue is often heterogeneous. Here, the authors create chamber-specific human pluripotent stem cell-derived cardiomyocytes to form both ventricular and atrial cells before embedding in collagen-based matrix to form ring-shaped engineered heart t...
Main Authors: | Idit Goldfracht, Stephanie Protze, Assad Shiti, Noga Setter, Amit Gruber, Naim Shaheen, Yulia Nartiss, Gordon Keller, Lior Gepstein |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-01-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-13868-x |
Similar Items
-
Reply to ‘Are atrial human pluripotent stem cell-derived cardiomyocytes ready to identify drugs that beat atrial fibrillation?’
by: Assad Shiti, et al.
Published: (2021-03-01) -
Optogenetic Control of Human Induced Pluripotent Stem Cell‐Derived Cardiac Tissue Models
by: Amit Gruber, et al.
Published: (2022-02-01) -
Optogenetic modulation of cardiac action potential properties may prevent arrhythmogenesis in short and long QT syndromes
by: Amit Gruber, et al.
Published: (2021-06-01) -
Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells
by: Shunsuke Funakoshi, et al.
Published: (2021-05-01) -
Calcium handling in human induced pluripotent stem cell derived cardiomyocytes.
by: Ilanit Itzhaki, et al.
Published: (2011-01-01)