The naked mole-rat has a functional purinergic pain pathway despite having a non-functional peptidergic pain pathway

The naked mole-rat has a functional purinergic pain pathway despite having a non-functional peptidergic pain pathway

Naked mole-rats (Heterocephalus glaber) have adaptations within their pain pathway that are beneficial to survival in large colonies within poorly ventilated burrow systems, with lower O2 and higher CO2 ambient levels than ground-level environments. These adaptations ultimately lead to a partial dis...

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Bibliographic Details
Main Authors: Brigitte M. Browe, Abigail R. Olsen, Cesar Ramirez, Rebecca H. Rickman, Ewan St. John Smith, Thomas J. Park
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Neurobiology of Pain
Subjects:
P2X3 receptor
Nociception
Naked mole-rat
Cannabinoid
purinergic C-fibers
Online Access:http://www.sciencedirect.com/science/article/pii/S2452073X20300052

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