Efficacy of extracellular vesicles from dental pulp stem cells for bone regeneration in rat calvarial bone defects

Efficacy of extracellular vesicles from dental pulp stem cells for bone regeneration in rat calvarial bone defects

Abstract Background Extracellular vesicles (EVs) are known to be secreted by various cells. In particular, mesenchymal stem cell (MSC)-derived EVs (MSC-EVs) have tissue repair capacity and anti-inflammatory properties. Dental pulp stem cells (DPSCs), which are MSCs isolated from pulp tissue, are les...

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Main Authors: Yuka Imanishi, Masaki Hata, Ryohei Matsukawa, Atsushi Aoyagi, Maiko Omi, Makoto Mizutani, Keiko Naruse, Shogo Ozawa, Masaki Honda, Tatsuaki Matsubara, Jun Takebe
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Inflammation and Regeneration
Subjects:
Dental pulp stem cells
Extracellular vesicles
Regenerative medicine
Bone defects
Online Access:https://doi.org/10.1186/s41232-021-00163-w

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