UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1

UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1

Abstract Background Exosomes are small vesicles released by cells, which have crucial functions in intercellular communication. Exosomes originated from cell membrane invagination and are released followed by multivesicular bodies (MVBs) fused with the cell membrane. It is known that Polymerase I an...

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Bibliographic Details
Main Authors: Xiaotong Cen, Qing Chen, Bin Wang, Hongjie Xu, Xu Wang, Yixia Ling, Xiaofei Zhang, Dajiang Qin
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Cell Communication and Signaling
Subjects:
Exosome secretion
PTRF/CAVIN1
SDPR/CAVIN2
UBE2O
Ubiquitination
Online Access:https://doi.org/10.1186/s12964-022-00996-z

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