XIAP 3′-untranslated region serves as a competitor for HMGA2 by arresting endogenous let-7a-5p in human hepatocellular carcinoma
X-linked inhibitor of apoptosis protein functions as an intrinsic regulator of apoptosis by inhibition of caspase activity and possesses a pivotal role in human cancer development and progression. A growing body of literature has demonstrated that microRNAs lead to the degradation or translational r...
Main Authors: | Wen-Yong Wu, Si-Qi Tao, Xiao-Nan Wang, Peter E Lobie, Zheng-Sheng Wu |
---|---|
Format: | Article |
Language: | English |
Published: |
IOS Press
2017-07-01
|
Series: | Tumor Biology |
Online Access: | https://doi.org/10.1177/1010428317719578 |
Similar Items
-
THE ROLE OF LET-7/HMGA2 LINKAGE IN THE PATHOGENESIS AND PROGNOSIS OF MYELODYSPLASTIC NEOPLASMS
by: D. Vlachopoulou, et al.
Published: (2024-01-01) -
let-7i inhibits proliferation and migration of bladder cancer cells by targeting HMGA1
by: M-M Qin, et al.
Published: (2019-06-01) -
Skeletal muscle differentiation evokes endogenous XIAP to restrict the apoptotic pathway.
by: Michelle I Smith, et al.
Published: (2009-01-01) -
Let-7 Represses Carcinogenesis and a Stem Cell Phenotype in the Intestine via Regulation of Hmga2.
by: Blair B Madison, et al.
Published: (2015-08-01) -
HMGA1-Regulating microRNAs Let-7a and miR-26a are Downregulated in Human Seminomas
by: Marco De Martino, et al.
Published: (2020-04-01)