Neuronal Gtf2i deletion alters mitochondrial and autophagic properties

Abstract Gtf2i encodes the general transcription factor II-I (TFII-I), with peak expression during pre-natal and early post-natal brain development stages. Because these stages are critical for proper brain development, we studied at the single-cell level the consequences of Gtf2i’s deletion from ex...

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Bibliographic Details
Main Authors: Ariel Nir Sade, Gilad Levy, Sari Schokoroy Trangle, Galit Elad Sfadia, Ela Bar, Omer Ophir, Inbar Fischer, May Rokach, Andrea Atzmon, Hadar Parnas, Tali Rosenberg, Asaf Marco, Orna Elroy Stein, Boaz Barak
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05612-5