Neuronal Gtf2i deletion alters mitochondrial and autophagic properties
Abstract Gtf2i encodes the general transcription factor II-I (TFII-I), with peak expression during pre-natal and early post-natal brain development stages. Because these stages are critical for proper brain development, we studied at the single-cell level the consequences of Gtf2i’s deletion from ex...
Main Authors: | , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-12-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-023-05612-5 |