Pseudo-Placentational Endometrial Hyperplasia in the Bitch: Case Series
Canine pseudo-placentational endometrial hyperplasia differs from the classical form of cystic endometrial hyperplasia for the well-organized tissue architecture resembling the canine placenta. After the discovery, it has been inconstantly reported. The present work reports the clinicopathological d...
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MDPI AG
2021-03-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/11/3/718 |
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| author | Gabriele Marino Alessandra Sfacteria Giuseppe Catone Antonina Zanghì Fabiana Pecchia Angela Difrancesco Marco Russo |
| author_facet | Gabriele Marino Alessandra Sfacteria Giuseppe Catone Antonina Zanghì Fabiana Pecchia Angela Difrancesco Marco Russo |
| author_sort | Gabriele Marino |
| collection | DOAJ |
| description | Canine pseudo-placentational endometrial hyperplasia differs from the classical form of cystic endometrial hyperplasia for the well-organized tissue architecture resembling the canine placenta. After the discovery, it has been inconstantly reported. The present work reports the clinicopathological details of six spontaneous cases retrieved retrospectively from a large database. The lesion was found in young non-pregnant female dogs (median 2.0 years) at the end of dioestrus. It could be imaged by ultrasound and was always grossly detectable as single or multiple uterine enlargements of 2–3 cm in diameter with a villous whitish tissue growing on the mucosa and occluding the lumen. Histology confirmed the tissue architecture of the canine placenta with a basal glandular layer, a connective band, a spongy layer and a tortuous and compact labyrinth, often poorly recognizable. The pseudo-placentational hyperplasia is a non-inflammatory proliferative lesion although numerous mast cells inhabit the connective band, and a superimposed inflammatory infiltrate was seen in a case. Canine pseudo-placentational endometrial hyperplasia has very peculiar features, and it is a model for canine placentation and may help to better understand the cystic endometrial hyperplasia/pyometra complex. |
| first_indexed | 2024-03-09T05:10:55Z |
| format | Article |
| id | doaj.art-4f7a91e88aa7435ca225fd7df7248d52 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-09T05:10:55Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-4f7a91e88aa7435ca225fd7df7248d522023-12-03T12:49:28ZengMDPI AGAnimals2076-26152021-03-0111371810.3390/ani11030718Pseudo-Placentational Endometrial Hyperplasia in the Bitch: Case SeriesGabriele Marino0Alessandra Sfacteria1Giuseppe Catone2Antonina Zanghì3Fabiana Pecchia4Angela Difrancesco5Marco Russo6Department of Veterinary Sciences, University of Messina, 98168 Messina, ItalyDepartment of Veterinary Sciences, University of Messina, 98168 Messina, ItalyDepartment of Veterinary Sciences, University of Messina, 98168 Messina, ItalyDepartment of Veterinary Sciences, University of Messina, 98168 Messina, ItalyDepartment of Veterinary Sciences, University of Messina, 98168 Messina, ItalyDepartment of Veterinary Sciences, University of Messina, 98168 Messina, ItalyDepartment of Veterinary Medicine and Animal Production, University of Naples, Federico II, 80137 Naples, ItalyCanine pseudo-placentational endometrial hyperplasia differs from the classical form of cystic endometrial hyperplasia for the well-organized tissue architecture resembling the canine placenta. After the discovery, it has been inconstantly reported. The present work reports the clinicopathological details of six spontaneous cases retrieved retrospectively from a large database. The lesion was found in young non-pregnant female dogs (median 2.0 years) at the end of dioestrus. It could be imaged by ultrasound and was always grossly detectable as single or multiple uterine enlargements of 2–3 cm in diameter with a villous whitish tissue growing on the mucosa and occluding the lumen. Histology confirmed the tissue architecture of the canine placenta with a basal glandular layer, a connective band, a spongy layer and a tortuous and compact labyrinth, often poorly recognizable. The pseudo-placentational hyperplasia is a non-inflammatory proliferative lesion although numerous mast cells inhabit the connective band, and a superimposed inflammatory infiltrate was seen in a case. Canine pseudo-placentational endometrial hyperplasia has very peculiar features, and it is a model for canine placentation and may help to better understand the cystic endometrial hyperplasia/pyometra complex.https://www.mdpi.com/2076-2615/11/3/718doguterusplacentapyometrahistology |
| spellingShingle | Gabriele Marino Alessandra Sfacteria Giuseppe Catone Antonina Zanghì Fabiana Pecchia Angela Difrancesco Marco Russo Pseudo-Placentational Endometrial Hyperplasia in the Bitch: Case Series Animals dog uterus placenta pyometra histology |
| title | Pseudo-Placentational Endometrial Hyperplasia in the Bitch: Case Series |
| title_full | Pseudo-Placentational Endometrial Hyperplasia in the Bitch: Case Series |
| title_fullStr | Pseudo-Placentational Endometrial Hyperplasia in the Bitch: Case Series |
| title_full_unstemmed | Pseudo-Placentational Endometrial Hyperplasia in the Bitch: Case Series |
| title_short | Pseudo-Placentational Endometrial Hyperplasia in the Bitch: Case Series |
| title_sort | pseudo placentational endometrial hyperplasia in the bitch case series |
| topic | dog uterus placenta pyometra histology |
| url | https://www.mdpi.com/2076-2615/11/3/718 |
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