Melatonin Alleviates Renal Injury in Mouse Model of Sepsis

Melatonin Alleviates Renal Injury in Mouse Model of Sepsis

Melatonin (N-acetyl-5-methoxytryptamine; MLT) has been shown to have a renal-protective effect against kidney injury. However, the mechanisms underlying the protective role of MLT in sepsis-induced renal injury are yet to be revealed. In this study, MLT alleviated renal dysfunction with the increase...

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Bibliographic Details
Main Authors: Liyang Chen, Zhijian Han, Zhiguang Shi, Chao Liu, Qiulun Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
melatonin
sepsis
ROS (reactive oxygen species)
acute kidney injury
renal dysfunction
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.697643/full

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