Identification and Mechanism of Action of the Global Secondary Metabolism Regulator SaraC in Stereum hirsutum

Identification and Mechanism of Action of the Global Secondary Metabolism Regulator SaraC in Stereum hirsutum

ABSTRACT DNA methylation is an important factor in the regulation of gene expression. In analyzing genomic data of Stereum hirsutum FP-91666, we found a hypothetical bifunctional transcription regulator/O6Meguanine-DNA methyltransferase (named SaraC), which is widely present in both bacteria and fun...

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Bibliographic Details
Main Authors: Qian-Yi Hu, Xue-Juan Pu, Guo-Hong Li, Chun-Qiang Li, Hong-Mei Lei, Ke-Qin Zhang, Pei-Ji Zhao
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:Microbiology Spectrum
Subjects:
DNA methylation
secondary metabolism
global regulator
methylome
transcriptome
metabolome
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02624-22

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