The genetic landscape and possible therapeutics of neurofibromatosis type 2

The genetic landscape and possible therapeutics of neurofibromatosis type 2

Abstract Neurofibromatosis type 2 (NF2) is a genetic condition marked by the development of multiple benign tumors in the nervous system. The most common tumors associated with NF2 are bilateral vestibular schwannoma, meningioma, and ependymoma. The clinical manifestations of NF2 depend on the site...

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Bibliographic Details
Main Authors: Mohammad Amin Ghalavand, Alimohamad Asghari, Mohammad Farhadi, Farzad Taghizadeh-Hesary, Masoud Garshasbi, Masoumeh Falah
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Cancer Cell International
Subjects:
Neurofibromatosis type 2
NF2
Merlin
Meningiomas
Vestibular schwannoma
Acoustic neuroma
Online Access:https://doi.org/10.1186/s12935-023-02940-8

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