Clinical predictive factors for vaginal delivery following induction of labour among pregnant women in Jordan
Abstract Background Induction of labour (IOL) is an important and common clinical procedure in obstetrics. In the current study, we evaluate predictors of vaginal delivery in both nulliparous and multiparous women in north Jordan who were induced with vaginal prostaglandins. Method A prospective stu...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2021-10-01
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| Series: | BMC Pregnancy and Childbirth |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12884-021-04151-3 |
| _version_ | 1818987236654317568 |
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| author | Rawan A. Obeidat Mahmoud Almaaitah Abeer Ben-Sadon Dina Istaiti Hasan Rawashdeh Shereen Hamadneh Hanan Hammouri Adel Bataineh |
| author_facet | Rawan A. Obeidat Mahmoud Almaaitah Abeer Ben-Sadon Dina Istaiti Hasan Rawashdeh Shereen Hamadneh Hanan Hammouri Adel Bataineh |
| author_sort | Rawan A. Obeidat |
| collection | DOAJ |
| description | Abstract Background Induction of labour (IOL) is an important and common clinical procedure in obstetrics. In the current study, we evaluate predictors of vaginal delivery in both nulliparous and multiparous women in north Jordan who were induced with vaginal prostaglandins. Method A prospective study was conducted on 530 pregnant women at King Abdullah University Hospital (KAUH) in north Jordan. All pregnant mothers with singleton live fetuses, who had induction of labour (IOL) between July 2017 and June 2019, were included in the study. Mode of delivery, whether vaginal or caesarean, was the primary outcome. Several maternal and fetal variables were investigated. The safety and benefit of repeated dosage of vaginal prostaglandin E2 (PGE2) tablets, neonatal outcomes and factors that affect duration of labour were also evaluated. Pearson χ2 test was used to investigate the significance of association between categorical variables, while student’s t-test and ANOVA were applied to examine the mean differences between categorical and numerical variables. Linear regression analysis was utilized to study the relation between two continuous variables. A multivariate regression analysis was then performed. Significance level was considered at alpha less than 0.05. Results Nulliparous women (N = 254) had significantly higher cesarean delivery rate (58.7% vs. 17.8%, p < 0.001) and longer duration of labour (16.1 ± 0.74 h vs. 11.0 ± 0.43 h, p < 0.001) than multiparous women (N = 276). In nulliparous women, the rate of vaginal delivery was significantly higher in women with higher Bishop score; the mean Bishop score was 3.47 ± 0.12 in nulliparous women who had vaginal delivery vs. 3.06 ± 0.10 in women who had cesarean delivery (Adjusted odds ratio (AOR) = 1.2, 95% CI: 1.03–1.28, p = 0.03). In multiparous women, the rate of vaginal delivery was significantly higher in women with higher Bishop scores and lower in women with higher body mass index (BMI). The mean Bishop score was 3.97 ± 0.07 in multiparous women who had vaginal delivery vs. 3.56 ± 0.16 in women who had cesarean delivery (AOR = 1.5, 95% CI: 1.1–2.1, p = 0.01). The mean BMI was 30.24 ± 0.28 kg/m2 in multiparous women who had vaginal delivery vs. 32.36 ± 0.73 kg/m2 in women who had cesarean delivery (AOR = 0.89, 95% CI: 0.84–0.96, p = 0.005). 27% of nulliparous women who received more than two PGE2 tablets and 50% of multiparous women who received more than two PGE2 tablets had vaginal delivery with no significant increase in neonatal morbidity. Conclusion Parity and cervical status are the main predictors of successful labour induction. Further studies are required to investigate the benefit of the use of additional doses of vaginal PGE2 above the recommended dose for IOL. |
| first_indexed | 2024-12-20T19:03:29Z |
| format | Article |
| id | doaj.art-4f83816ee70842fc869b32fa63ad14ff |
| institution | Directory Open Access Journal |
| issn | 1471-2393 |
| language | English |
| last_indexed | 2024-12-20T19:03:29Z |
| publishDate | 2021-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pregnancy and Childbirth |
| spelling | doaj.art-4f83816ee70842fc869b32fa63ad14ff2022-12-21T19:29:20ZengBMCBMC Pregnancy and Childbirth1471-23932021-10-0121111010.1186/s12884-021-04151-3Clinical predictive factors for vaginal delivery following induction of labour among pregnant women in JordanRawan A. Obeidat0Mahmoud Almaaitah1Abeer Ben-Sadon2Dina Istaiti3Hasan Rawashdeh4Shereen Hamadneh5Hanan Hammouri6Adel Bataineh7Department of Obstetrics and Gynecology, Faculty of Medicine, Jordan University of Science and Technology, King Abdullah University HospitalDepartment of Obstetrics and Gynecology, Faculty of Medicine, Jordan University of Science and Technology, King Abdullah University HospitalDepartment of Obstetrics and Gynecology, Faculty of Medicine, Jordan University of Science and Technology, King Abdullah University HospitalDepartment of Obstetrics and Gynecology, Faculty of Medicine, Jordan University of Science and Technology, King Abdullah University HospitalDepartment of Obstetrics and Gynecology, Faculty of Medicine, Jordan University of Science and Technology, King Abdullah University HospitalDepartment of Maternal and Child Health, Al Al-Bayt UniversityDepartment of Mathematics and Statistics, Jordan University of Science and TechnologyDepartment of Anesthesia, Jordan University of Science and TechnologyAbstract Background Induction of labour (IOL) is an important and common clinical procedure in obstetrics. In the current study, we evaluate predictors of vaginal delivery in both nulliparous and multiparous women in north Jordan who were induced with vaginal prostaglandins. Method A prospective study was conducted on 530 pregnant women at King Abdullah University Hospital (KAUH) in north Jordan. All pregnant mothers with singleton live fetuses, who had induction of labour (IOL) between July 2017 and June 2019, were included in the study. Mode of delivery, whether vaginal or caesarean, was the primary outcome. Several maternal and fetal variables were investigated. The safety and benefit of repeated dosage of vaginal prostaglandin E2 (PGE2) tablets, neonatal outcomes and factors that affect duration of labour were also evaluated. Pearson χ2 test was used to investigate the significance of association between categorical variables, while student’s t-test and ANOVA were applied to examine the mean differences between categorical and numerical variables. Linear regression analysis was utilized to study the relation between two continuous variables. A multivariate regression analysis was then performed. Significance level was considered at alpha less than 0.05. Results Nulliparous women (N = 254) had significantly higher cesarean delivery rate (58.7% vs. 17.8%, p < 0.001) and longer duration of labour (16.1 ± 0.74 h vs. 11.0 ± 0.43 h, p < 0.001) than multiparous women (N = 276). In nulliparous women, the rate of vaginal delivery was significantly higher in women with higher Bishop score; the mean Bishop score was 3.47 ± 0.12 in nulliparous women who had vaginal delivery vs. 3.06 ± 0.10 in women who had cesarean delivery (Adjusted odds ratio (AOR) = 1.2, 95% CI: 1.03–1.28, p = 0.03). In multiparous women, the rate of vaginal delivery was significantly higher in women with higher Bishop scores and lower in women with higher body mass index (BMI). The mean Bishop score was 3.97 ± 0.07 in multiparous women who had vaginal delivery vs. 3.56 ± 0.16 in women who had cesarean delivery (AOR = 1.5, 95% CI: 1.1–2.1, p = 0.01). The mean BMI was 30.24 ± 0.28 kg/m2 in multiparous women who had vaginal delivery vs. 32.36 ± 0.73 kg/m2 in women who had cesarean delivery (AOR = 0.89, 95% CI: 0.84–0.96, p = 0.005). 27% of nulliparous women who received more than two PGE2 tablets and 50% of multiparous women who received more than two PGE2 tablets had vaginal delivery with no significant increase in neonatal morbidity. Conclusion Parity and cervical status are the main predictors of successful labour induction. Further studies are required to investigate the benefit of the use of additional doses of vaginal PGE2 above the recommended dose for IOL.https://doi.org/10.1186/s12884-021-04151-3Induction of labourParityProstaglandin E2Bishop scoreCesarean section |
| spellingShingle | Rawan A. Obeidat Mahmoud Almaaitah Abeer Ben-Sadon Dina Istaiti Hasan Rawashdeh Shereen Hamadneh Hanan Hammouri Adel Bataineh Clinical predictive factors for vaginal delivery following induction of labour among pregnant women in Jordan BMC Pregnancy and Childbirth Induction of labour Parity Prostaglandin E2 Bishop score Cesarean section |
| title | Clinical predictive factors for vaginal delivery following induction of labour among pregnant women in Jordan |
| title_full | Clinical predictive factors for vaginal delivery following induction of labour among pregnant women in Jordan |
| title_fullStr | Clinical predictive factors for vaginal delivery following induction of labour among pregnant women in Jordan |
| title_full_unstemmed | Clinical predictive factors for vaginal delivery following induction of labour among pregnant women in Jordan |
| title_short | Clinical predictive factors for vaginal delivery following induction of labour among pregnant women in Jordan |
| title_sort | clinical predictive factors for vaginal delivery following induction of labour among pregnant women in jordan |
| topic | Induction of labour Parity Prostaglandin E2 Bishop score Cesarean section |
| url | https://doi.org/10.1186/s12884-021-04151-3 |
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