Asthma medication adherence, control, and psychological symptoms: a cross-sectional study
Abstract Background Nonadherence to therapies and psychological disorders are associated with poor asthma control. This study aims to assess the prevalence of anxiety and depressive symptoms, asthma control, and adherence to inhalers and to investigate whether there is an association of anxiety and...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2024-04-01
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| Series: | BMC Pulmonary Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12890-024-02995-x |
| _version_ | 1797199669422456832 |
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| author | Abdullah A. Alqarni Abdulelah M. Aldhahir Rayan A. Siraj Jaber S. Alqahtani Dana A. Alghamdi Sarah K. Alghamdi Abeer A. Alamoudi Majduleen A. Mohtaseb Mansour Majrshi Abdulkareem A. AlGarni Omaima I. Badr Hassan Alwafi |
| author_facet | Abdullah A. Alqarni Abdulelah M. Aldhahir Rayan A. Siraj Jaber S. Alqahtani Dana A. Alghamdi Sarah K. Alghamdi Abeer A. Alamoudi Majduleen A. Mohtaseb Mansour Majrshi Abdulkareem A. AlGarni Omaima I. Badr Hassan Alwafi |
| author_sort | Abdullah A. Alqarni |
| collection | DOAJ |
| description | Abstract Background Nonadherence to therapies and psychological disorders are associated with poor asthma control. This study aims to assess the prevalence of anxiety and depressive symptoms, asthma control, and adherence to inhalers and to investigate whether there is an association of anxiety and depressive symptoms with adherence to inhalers and asthma control. Methods We measured anxiety and depressive symptoms using the Hospital Anxiety and Depression Scale in patients with asthma. Asthma Control Test and the 10-Item Test of Adherence to Inhalers Scale were used to assess levels of asthma control adherence to inhalers, respectively. Univariate and multivariate regression models assessed the associations of anxiety and depressive symptoms with adherence to inhalers and asthma control. Results A total of 287 patients completed the study, of whom 72% were female. The mean ± SD age and body mass index of our study population were 44 ± 13 years and 29 ± 7.2 kg/m2, respectively. Poor adherence to inhaler use was highly prevalent (49.8%; 95% CI: 43.8 to 55.7). The prevalence of anxiety, depression and poor asthma control was 27.2% (95% CI: 22.1 to 32.7), 20.9% (95% CI: 16.3 to 26.1), and 22.7% (95% CI: 17.9 to 27.9), respectively. We found a negative relationship between asthma control and anxiety, and depressive symptoms (adjusted β: -0.25; 95% CI: -0.36 to -0.14; p < 0.001 and adjusted β: -0.29; 95% CI: -0.40 to -0.18; p < 0.001, respectively). A negative relationship was also observed between adherence to inhalers and anxiety and depressive symptoms (adjusted β: -0.34; 95% CI: -0.46 to -0.22; p < 0.001 and adjusted β: -0.36; 95% CI: − 0.48 to − 0.24; p < 0.001, respectively). Conclusions The high prevalence of uncontrolled asthma symptoms and poor adherence to inhalers and their impact on anxiety and depression levels among patients with asthma point to the need for early screening for psychological symptoms and recognition of nonadherence as part of asthma assessment and management plan in primary care in Saudi Arabia to avoid further worsening of asthma symptoms. Further studies are needed to explore the effectiveness of specific psychoeducational interventions and investigate the long-term impact of early psychological symptom detection on asthma outcomes. |
| first_indexed | 2024-04-24T07:19:26Z |
| format | Article |
| id | doaj.art-4f8545e535874b7f9efe212e5bc90798 |
| institution | Directory Open Access Journal |
| issn | 1471-2466 |
| language | English |
| last_indexed | 2024-04-24T07:19:26Z |
| publishDate | 2024-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pulmonary Medicine |
| spelling | doaj.art-4f8545e535874b7f9efe212e5bc907982024-04-21T11:07:30ZengBMCBMC Pulmonary Medicine1471-24662024-04-0124111010.1186/s12890-024-02995-xAsthma medication adherence, control, and psychological symptoms: a cross-sectional studyAbdullah A. Alqarni0Abdulelah M. Aldhahir1Rayan A. Siraj2Jaber S. Alqahtani3Dana A. Alghamdi4Sarah K. Alghamdi5Abeer A. Alamoudi6Majduleen A. Mohtaseb7Mansour Majrshi8Abdulkareem A. AlGarni9Omaima I. Badr10Hassan Alwafi11Department of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz UniversityRespiratory Therapy Department, Faculty of Applied Medical Sciences, Jazan UniversityDepartment of Respiratory Care, College of Applied Medical Sciences, King Faisal UniversityDepartment of Respiratory Care, Prince Sultan Military College of Health SciencesDepartment of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz UniversityDepartment of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz UniversityDepartment of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz UniversityDepartment of Respiratory Therapy, Faculty of Medical Rehabilitation Sciences, King Abdulaziz UniversityNational Heart and Lung Institute, Imperial College LondonKing Abdulaziz Hospital, The Ministry of National Guard Health AffairsDepartment of Chest Medicine, Faculty of Medicine, Mansoura UniversityDepartment of Clinical Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura UniversityAbstract Background Nonadherence to therapies and psychological disorders are associated with poor asthma control. This study aims to assess the prevalence of anxiety and depressive symptoms, asthma control, and adherence to inhalers and to investigate whether there is an association of anxiety and depressive symptoms with adherence to inhalers and asthma control. Methods We measured anxiety and depressive symptoms using the Hospital Anxiety and Depression Scale in patients with asthma. Asthma Control Test and the 10-Item Test of Adherence to Inhalers Scale were used to assess levels of asthma control adherence to inhalers, respectively. Univariate and multivariate regression models assessed the associations of anxiety and depressive symptoms with adherence to inhalers and asthma control. Results A total of 287 patients completed the study, of whom 72% were female. The mean ± SD age and body mass index of our study population were 44 ± 13 years and 29 ± 7.2 kg/m2, respectively. Poor adherence to inhaler use was highly prevalent (49.8%; 95% CI: 43.8 to 55.7). The prevalence of anxiety, depression and poor asthma control was 27.2% (95% CI: 22.1 to 32.7), 20.9% (95% CI: 16.3 to 26.1), and 22.7% (95% CI: 17.9 to 27.9), respectively. We found a negative relationship between asthma control and anxiety, and depressive symptoms (adjusted β: -0.25; 95% CI: -0.36 to -0.14; p < 0.001 and adjusted β: -0.29; 95% CI: -0.40 to -0.18; p < 0.001, respectively). A negative relationship was also observed between adherence to inhalers and anxiety and depressive symptoms (adjusted β: -0.34; 95% CI: -0.46 to -0.22; p < 0.001 and adjusted β: -0.36; 95% CI: − 0.48 to − 0.24; p < 0.001, respectively). Conclusions The high prevalence of uncontrolled asthma symptoms and poor adherence to inhalers and their impact on anxiety and depression levels among patients with asthma point to the need for early screening for psychological symptoms and recognition of nonadherence as part of asthma assessment and management plan in primary care in Saudi Arabia to avoid further worsening of asthma symptoms. Further studies are needed to explore the effectiveness of specific psychoeducational interventions and investigate the long-term impact of early psychological symptom detection on asthma outcomes.https://doi.org/10.1186/s12890-024-02995-xAsthmaDepressionAnxietyAdherence to inhalerAsthma controlAdherence to controller therapies |
| spellingShingle | Abdullah A. Alqarni Abdulelah M. Aldhahir Rayan A. Siraj Jaber S. Alqahtani Dana A. Alghamdi Sarah K. Alghamdi Abeer A. Alamoudi Majduleen A. Mohtaseb Mansour Majrshi Abdulkareem A. AlGarni Omaima I. Badr Hassan Alwafi Asthma medication adherence, control, and psychological symptoms: a cross-sectional study BMC Pulmonary Medicine Asthma Depression Anxiety Adherence to inhaler Asthma control Adherence to controller therapies |
| title | Asthma medication adherence, control, and psychological symptoms: a cross-sectional study |
| title_full | Asthma medication adherence, control, and psychological symptoms: a cross-sectional study |
| title_fullStr | Asthma medication adherence, control, and psychological symptoms: a cross-sectional study |
| title_full_unstemmed | Asthma medication adherence, control, and psychological symptoms: a cross-sectional study |
| title_short | Asthma medication adherence, control, and psychological symptoms: a cross-sectional study |
| title_sort | asthma medication adherence control and psychological symptoms a cross sectional study |
| topic | Asthma Depression Anxiety Adherence to inhaler Asthma control Adherence to controller therapies |
| url | https://doi.org/10.1186/s12890-024-02995-x |
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