The influence of the initial state of nutrition on the lifespan of patients with amyotrophic lateral sclerosis (ALS) during home enteral nutrition
Aim: Amyotrophic lateral sclerosis (ALS) is a chronic, neurodegenerative disease, which leads to development of malnutrition. The main purpose of this research was to analyze the impact of malnutrition on the course of the disease and long-term survival. Material and methods: A retrospective analysi...
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| Format: | Article |
| Language: | English |
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Arán Ediciones, S. L.
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| Series: | Nutrición Hospitalaria |
| Subjects: | |
| Online Access: | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112016000100002&lng=en&tlng=en |
| _version_ | 1819227738220789760 |
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| author | Janusz Sznajder Marta Ślefarska-Wasilęwska Stanisław Kłęk |
| author_facet | Janusz Sznajder Marta Ślefarska-Wasilęwska Stanisław Kłęk |
| author_sort | Janusz Sznajder |
| collection | DOAJ |
| description | Aim: Amyotrophic lateral sclerosis (ALS) is a chronic, neurodegenerative disease, which leads to development of malnutrition. The main purpose of this research was to analyze the impact of malnutrition on the course of the disease and long-term survival. Material and methods: A retrospective analysis has been performed on 48 patients (22 F [45,83%] and 26 M [54,17%], the average age of patients: 66,2 [43-83]) in 2008-2014.The analysis of the initial state of nutrition was measured by body mass index (BMI), nutritional status according to NRS 2002, SGA and concentration of albumin in blood serum. Patients were divided into two groups, depending on the state of nutrition: well-nourished and malnourished. The groups were created separately for each of these, which allowed an additional comparative analysis of techniques used for the assessment of nutritional status. Results: Proper state of nutrition was interrelated with longer survival (SGA: 456 vs. 679 days, NRS: 312 vs. 659 vs. 835 days, BMI: respectively, 411, 541, 631 days, results were statistically significant for NRS and BMI). Concentration of albumin was not a prognostic factor, but longer survival was observed when level of albumin was increased during nutritional therapy. Conclusions: The initial nutrition state and positive response to enteral feeding is associated with better survival among patients with ALS. For this reason, nutritional therapy should be introduced as soon as possible. |
| first_indexed | 2024-12-23T10:46:09Z |
| format | Article |
| id | doaj.art-4f8b0dc7d6884b8ba3303cd5a25628b2 |
| institution | Directory Open Access Journal |
| issn | 0212-1611 |
| language | English |
| last_indexed | 2024-12-23T10:46:09Z |
| publisher | Arán Ediciones, S. L. |
| record_format | Article |
| series | Nutrición Hospitalaria |
| spelling | doaj.art-4f8b0dc7d6884b8ba3303cd5a25628b22022-12-21T17:50:01ZengArán Ediciones, S. L.Nutrición Hospitalaria0212-16113313710.20960/nh.7S0212-16112016000100002The influence of the initial state of nutrition on the lifespan of patients with amyotrophic lateral sclerosis (ALS) during home enteral nutritionJanusz Sznajder0Marta Ślefarska-Wasilęwska1Stanisław Kłęk2Nutrimed Nutrition ClinicNutrimed Nutrition ClinicNutrimed Nutrition ClinicAim: Amyotrophic lateral sclerosis (ALS) is a chronic, neurodegenerative disease, which leads to development of malnutrition. The main purpose of this research was to analyze the impact of malnutrition on the course of the disease and long-term survival. Material and methods: A retrospective analysis has been performed on 48 patients (22 F [45,83%] and 26 M [54,17%], the average age of patients: 66,2 [43-83]) in 2008-2014.The analysis of the initial state of nutrition was measured by body mass index (BMI), nutritional status according to NRS 2002, SGA and concentration of albumin in blood serum. Patients were divided into two groups, depending on the state of nutrition: well-nourished and malnourished. The groups were created separately for each of these, which allowed an additional comparative analysis of techniques used for the assessment of nutritional status. Results: Proper state of nutrition was interrelated with longer survival (SGA: 456 vs. 679 days, NRS: 312 vs. 659 vs. 835 days, BMI: respectively, 411, 541, 631 days, results were statistically significant for NRS and BMI). Concentration of albumin was not a prognostic factor, but longer survival was observed when level of albumin was increased during nutritional therapy. Conclusions: The initial nutrition state and positive response to enteral feeding is associated with better survival among patients with ALS. For this reason, nutritional therapy should be introduced as soon as possible.http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112016000100002&lng=en&tlng=enEsclerosis lateral amiotróficaDesnutriciónAlimentación enteral lateral |
| spellingShingle | Janusz Sznajder Marta Ślefarska-Wasilęwska Stanisław Kłęk The influence of the initial state of nutrition on the lifespan of patients with amyotrophic lateral sclerosis (ALS) during home enteral nutrition Nutrición Hospitalaria Esclerosis lateral amiotrófica Desnutrición Alimentación enteral lateral |
| title | The influence of the initial state of nutrition on the lifespan of patients with amyotrophic lateral sclerosis (ALS) during home enteral nutrition |
| title_full | The influence of the initial state of nutrition on the lifespan of patients with amyotrophic lateral sclerosis (ALS) during home enteral nutrition |
| title_fullStr | The influence of the initial state of nutrition on the lifespan of patients with amyotrophic lateral sclerosis (ALS) during home enteral nutrition |
| title_full_unstemmed | The influence of the initial state of nutrition on the lifespan of patients with amyotrophic lateral sclerosis (ALS) during home enteral nutrition |
| title_short | The influence of the initial state of nutrition on the lifespan of patients with amyotrophic lateral sclerosis (ALS) during home enteral nutrition |
| title_sort | influence of the initial state of nutrition on the lifespan of patients with amyotrophic lateral sclerosis als during home enteral nutrition |
| topic | Esclerosis lateral amiotrófica Desnutrición Alimentación enteral lateral |
| url | http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112016000100002&lng=en&tlng=en |
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