Gastric T-cell lymphoma associated with hemophagocytic syndrome

<p>Abstract</p> <p>Background</p> <p>Lymphoma-associated hemophagocytic syndrome (LAHS) occurs in mostly extra nodal non-Hodgkin's lymphoma. LAHS arising from gastrointestinal lymphoma has never been reported. Here we report a case of gastric T-cell lymphoma-associ...

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Main Authors: Yanai Yoshiyuki, Ohno Keisuke, Homma Toshio, Sato Masaaki, Kasai Kiyoshi, Okazaki Minoru, Denno Ryuuichi, Yasoshima Takahiro, Hata Fumitake, Fukui Rika, Sogahata Katsuya, Nishimori Hidefumi, Hirata Koichi
Format: Article
Language:English
Published: BMC 2004-10-01
Series:World Journal of Surgical Oncology
Online Access:http://www.wjso.com/content/2/1/34
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Summary:<p>Abstract</p> <p>Background</p> <p>Lymphoma-associated hemophagocytic syndrome (LAHS) occurs in mostly extra nodal non-Hodgkin's lymphoma. LAHS arising from gastrointestinal lymphoma has never been reported. Here we report a case of gastric T-cell lymphoma-associated hemophagocytic syndrome.</p> <p>Case presentation</p> <p>A 51-year-old woman presented with pain, redness of breasts, fever and hematemesis. Hematological examination revealed anemia. Gastroscopy revealed small bleeding ulcers in the stomach and the computed tomography scan showed liver tumor. She underwent total gastrectomy for gastrointestinal bleeding and the histopathology revealed gastric T-cell lymphoma. She continued to bleed from the anastomosis and died on the 8th postoperative day. Autopsy revealed it to be a LAHS.</p> <p>Conclusions</p> <p>If Hemophagocytic syndrome (HPS) occurs in lymphoma of the gastrointestinal tract, bleeding from the primary lesion might be uncontrollable. Early diagnosis and appropriate treatment are needed for long-term survival.</p>
ISSN:1477-7819