TGF-β in pancreatic cancer initiation and progression: two sides of the same coin

TGF-β in pancreatic cancer initiation and progression: two sides of the same coin

Abstract Pancreatic cancer is highly lethal malignant tumor with characterised rapid progression, invasiveness and resistance to radiochemotherapy. Transforming growth factor-β (TGF-β) signaling plays a dual role in both pro-tumorigenic and tumor suppressive of pancreatic cancer, depending on tumor...

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Bibliographic Details
Main Authors: Wei Shen, Guo-qing Tao, Yu Zhang, Bing Cai, Jian Sun, Zhi-qiang Tian
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Cell & Bioscience
Subjects:
Transforming growth factor-β
Pancreatic cancer
Tumor microenvironment
Online Access:http://link.springer.com/article/10.1186/s13578-017-0168-0

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