Correlation between some immunological parameters and clinical presentation in RA patients
Background: Complement (C) & CRP in patients with Rheumatoid arthritis (RA)'could be trigger disease activity. Aim: To study the correlation between C, CRP, IgM,, IgG, IgA & some clinical presentation in RA patients. Methods: Latex agglutination test(AG) & single radial immunoassay(...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
College of Medicine University of Baghdad
2008-07-01
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| Series: | مجلة كلية الطب |
| Subjects: | |
| Online Access: | http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1288 |
| Summary: | Background: Complement (C) & CRP in patients with Rheumatoid arthritis (RA)'could be trigger disease activity.
Aim: To study the correlation between C, CRP, IgM,, IgG, IgA & some clinical presentation in RA patients.
Methods: Latex agglutination test(AG) & single radial immunoassay(SRIA) were used to asses CRP, IgMJgGJgA,, C, in 74 patients with RA.
Results: IgA & IgG were significantly increased, while the mean ofC3, C4 were slightly elevated in RA patients .
Conclusion: There is correlation between IgG and IgM with joint deformity and joint swelling respectively, while C3 was showed statistically significant P<0.01 with joint
stiffness, joint swelling and Rheumatoid nodule, where as CRP was statistically significant P<0.01withjoint swelling.. Key words : RA.C.CRP, IgM, IgG, IgA, SRI A,
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| ISSN: | 0041-9419 2410-8057 |