Correlation between some immunological parameters and clinical presentation in RA patients

Background: Complement (C) & CRP in patients with Rheumatoid arthritis (RA)'could be trigger disease activity. Aim: To study the correlation between C, CRP, IgM,, IgG, IgA & some clinical presentation in RA patients. Methods: Latex agglutination test(AG) & single radial immunoassay(...

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Main Authors: Nahida R. Abbas, Eman Sh. AL- Obeidy, Samira N. AL- Naim, Ali E. Kadim
Format: Article
Language:English
Published: College of Medicine University of Baghdad 2008-07-01
Series:مجلة كلية الطب
Subjects:
Online Access:http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1288
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author Nahida R. Abbas
Eman Sh. AL- Obeidy
Samira N. AL- Naim
Ali E. Kadim
author_facet Nahida R. Abbas
Eman Sh. AL- Obeidy
Samira N. AL- Naim
Ali E. Kadim
author_sort Nahida R. Abbas
collection DOAJ
description Background: Complement (C) & CRP in patients with Rheumatoid arthritis (RA)'could be trigger disease activity. Aim: To study the correlation between C, CRP, IgM,, IgG, IgA & some clinical presentation in RA patients. Methods: Latex agglutination test(AG) & single radial immunoassay(SRIA) were used to asses CRP, IgMJgGJgA,, C, in 74 patients with RA. Results: IgA & IgG were significantly increased, while the mean ofC3, C4 were slightly elevated in RA patients . Conclusion: There is correlation between IgG and IgM with joint deformity and joint swelling respectively, while C3 was showed statistically significant P<0.01 with joint stiffness, joint swelling and Rheumatoid nodule, where as CRP was statistically significant P<0.01withjoint swelling.. Key words : RA.C.CRP, IgM, IgG, IgA, SRI A, AG.
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spelling doaj.art-4f93721af71e47c5adda8d27e7fcdc6f2024-01-02T11:45:12ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572008-07-0150210.32007/1288%g235-240Correlation between some immunological parameters and clinical presentation in RA patientsNahida R. Abbas0Eman Sh. AL- Obeidy1Samira N. AL- Naim2Ali E. Kadim3Immunology,Institute of medical technology/Al-Mansor.Immunology, Medical city,Microbiology,Institute of medical technology/Al-Mansor.Microbiology,Institute of medical technology/Al-Mansor.Background: Complement (C) & CRP in patients with Rheumatoid arthritis (RA)'could be trigger disease activity. Aim: To study the correlation between C, CRP, IgM,, IgG, IgA & some clinical presentation in RA patients. Methods: Latex agglutination test(AG) & single radial immunoassay(SRIA) were used to asses CRP, IgMJgGJgA,, C, in 74 patients with RA. Results: IgA & IgG were significantly increased, while the mean ofC3, C4 were slightly elevated in RA patients . Conclusion: There is correlation between IgG and IgM with joint deformity and joint swelling respectively, while C3 was showed statistically significant P<0.01 with joint stiffness, joint swelling and Rheumatoid nodule, where as CRP was statistically significant P<0.01withjoint swelling.. Key words : RA.C.CRP, IgM, IgG, IgA, SRI A, AG.http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1288immunological parameters and clinical presentation
spellingShingle Nahida R. Abbas
Eman Sh. AL- Obeidy
Samira N. AL- Naim
Ali E. Kadim
Correlation between some immunological parameters and clinical presentation in RA patients
مجلة كلية الطب
immunological parameters and clinical presentation
title Correlation between some immunological parameters and clinical presentation in RA patients
title_full Correlation between some immunological parameters and clinical presentation in RA patients
title_fullStr Correlation between some immunological parameters and clinical presentation in RA patients
title_full_unstemmed Correlation between some immunological parameters and clinical presentation in RA patients
title_short Correlation between some immunological parameters and clinical presentation in RA patients
title_sort correlation between some immunological parameters and clinical presentation in ra patients
topic immunological parameters and clinical presentation
url http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1288
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AT emanshalobeidy correlationbetweensomeimmunologicalparametersandclinicalpresentationinrapatients
AT samiranalnaim correlationbetweensomeimmunologicalparametersandclinicalpresentationinrapatients
AT aliekadim correlationbetweensomeimmunologicalparametersandclinicalpresentationinrapatients