Methylocystis sp. Strain SC2 Acclimatizes to Increasing NH4+ Levels by a Precise Rebalancing of Enzymes and Osmolyte Composition

Methylocystis sp. Strain SC2 Acclimatizes to Increasing NH4+ Levels by a Precise Rebalancing of Enzymes and Osmolyte Composition

ABSTRACT A high NH4+ load is known to inhibit bacterial methane oxidation. This is due to a competition between CH4 and NH3 for the active site of particulate methane monooxygenase (pMMO), which converts CH4 to CH3OH. Here, we combined global proteomics with amino acid profiling and nitrogen oxides...

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Bibliographic Details
Main Authors: Kangli Guo, Anna Hakobyan, Timo Glatter, Nicole Paczia, Werner Liesack
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:mSystems
Subjects:
methanotrophs
Methylocystis
methane
ammonia
particulate methane monooxygenase
hydroxylamine oxidoreductase
Online Access:https://journals.asm.org/doi/10.1128/msystems.00403-22

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