Association between Dietary Inflammatory Index and Risk of Colorectal Adenomatous Polyps in Kashgar Prefecture of Xinjiang, China
Malignant colorectal tumors and precancerous lesions are closely associated with chronic inflammation. Specific dietary patterns can increase chronic inflammation in the body, thereby promoting the occurrence of tumors and precancerous lesions. We have conducted a case–control study in Kashgar Prefe...
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MDPI AG
2023-09-01
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| Online Access: | https://www.mdpi.com/2072-6643/15/18/4067 |
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| author | Zhuo-Jie He Weili Yusufu Shuang Zhang Min-Yi Luo Yong-Cheng Chen Hui Peng Xing-Yang Wan |
| author_facet | Zhuo-Jie He Weili Yusufu Shuang Zhang Min-Yi Luo Yong-Cheng Chen Hui Peng Xing-Yang Wan |
| author_sort | Zhuo-Jie He |
| collection | DOAJ |
| description | Malignant colorectal tumors and precancerous lesions are closely associated with chronic inflammation. Specific dietary patterns can increase chronic inflammation in the body, thereby promoting the occurrence of tumors and precancerous lesions. We have conducted a case–control study in Kashgar Prefecture, Xinjiang, China, to explore the association between the energy-adjusted dietary inflammatory index (E-DII) and the risk of colorectal adenomatous polyps (CAP). A total of 52 newly diagnosed patients with CAP and 192 controls at the First People’s Hospital of Kashgar Prefecture were enrolled in this study. Dietary information was collected using a food frequency questionnaire. The E-DII was calculated based on dietary data, reflecting an individual’s dietary inflammatory potential. Logistic regression models were used to evaluate the relationship between the E-DII and the risk of CAP, with adjustments for potential confounding factors. The results showed that the maximum anti- and pro-inflammatory values of E-DII were −4.33 and +3.48, respectively. Higher E-DII scores were associated with an increased risk of CAP, and this association remained statistically significant after adjusting for age, sex, body mass index, smoking status, and other relevant variables. Notably, a more pro-inflammatory dietary pattern may be related to an increased risk of developing CAP in Kashgar Prefecture. |
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| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T22:19:15Z |
| publishDate | 2023-09-01 |
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| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-4f9681f0c2694b4c99ef0b0c16085d722023-11-19T12:19:55ZengMDPI AGNutrients2072-66432023-09-011518406710.3390/nu15184067Association between Dietary Inflammatory Index and Risk of Colorectal Adenomatous Polyps in Kashgar Prefecture of Xinjiang, ChinaZhuo-Jie He0Weili Yusufu1Shuang Zhang2Min-Yi Luo3Yong-Cheng Chen4Hui Peng5Xing-Yang Wan6Department of General Surgery (Anorectal Surgery), The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510655, ChinaDepartment of Rectal Surgery, The First Hospital of Kashgar Prefecture, Kashgar 844000, ChinaDepartment of General Surgery (Anorectal Surgery), The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510655, ChinaDepartment of General Surgery (Anorectal Surgery), The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510655, ChinaGuangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510655, ChinaDepartment of General Surgery (Anorectal Surgery), The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510655, ChinaDepartment of General Surgery (Anorectal Surgery), The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510655, ChinaMalignant colorectal tumors and precancerous lesions are closely associated with chronic inflammation. Specific dietary patterns can increase chronic inflammation in the body, thereby promoting the occurrence of tumors and precancerous lesions. We have conducted a case–control study in Kashgar Prefecture, Xinjiang, China, to explore the association between the energy-adjusted dietary inflammatory index (E-DII) and the risk of colorectal adenomatous polyps (CAP). A total of 52 newly diagnosed patients with CAP and 192 controls at the First People’s Hospital of Kashgar Prefecture were enrolled in this study. Dietary information was collected using a food frequency questionnaire. The E-DII was calculated based on dietary data, reflecting an individual’s dietary inflammatory potential. Logistic regression models were used to evaluate the relationship between the E-DII and the risk of CAP, with adjustments for potential confounding factors. The results showed that the maximum anti- and pro-inflammatory values of E-DII were −4.33 and +3.48, respectively. Higher E-DII scores were associated with an increased risk of CAP, and this association remained statistically significant after adjusting for age, sex, body mass index, smoking status, and other relevant variables. Notably, a more pro-inflammatory dietary pattern may be related to an increased risk of developing CAP in Kashgar Prefecture.https://www.mdpi.com/2072-6643/15/18/4067colorectal adenomatous polypdietary inflammation indexdietinflammationKashgar Prefecture |
| spellingShingle | Zhuo-Jie He Weili Yusufu Shuang Zhang Min-Yi Luo Yong-Cheng Chen Hui Peng Xing-Yang Wan Association between Dietary Inflammatory Index and Risk of Colorectal Adenomatous Polyps in Kashgar Prefecture of Xinjiang, China Nutrients colorectal adenomatous polyp dietary inflammation index diet inflammation Kashgar Prefecture |
| title | Association between Dietary Inflammatory Index and Risk of Colorectal Adenomatous Polyps in Kashgar Prefecture of Xinjiang, China |
| title_full | Association between Dietary Inflammatory Index and Risk of Colorectal Adenomatous Polyps in Kashgar Prefecture of Xinjiang, China |
| title_fullStr | Association between Dietary Inflammatory Index and Risk of Colorectal Adenomatous Polyps in Kashgar Prefecture of Xinjiang, China |
| title_full_unstemmed | Association between Dietary Inflammatory Index and Risk of Colorectal Adenomatous Polyps in Kashgar Prefecture of Xinjiang, China |
| title_short | Association between Dietary Inflammatory Index and Risk of Colorectal Adenomatous Polyps in Kashgar Prefecture of Xinjiang, China |
| title_sort | association between dietary inflammatory index and risk of colorectal adenomatous polyps in kashgar prefecture of xinjiang china |
| topic | colorectal adenomatous polyp dietary inflammation index diet inflammation Kashgar Prefecture |
| url | https://www.mdpi.com/2072-6643/15/18/4067 |
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