Does Bacillus anthracis Lethal Toxin Directly Depress Myocardial Function? A Review of Clinical Cases and Preclinical Studies

Does Bacillus anthracis Lethal Toxin Directly Depress Myocardial Function? A Review of Clinical Cases and Preclinical Studies

The US outbreak of B.anthracis infection in 2001 and subsequent cases in the US and Europe demonstrate that anthrax is a continuing risk for the developed world. While several bacterial components contribute to the pathogenesis of B. anthracis, production of lethal toxin (LT) is strongly associated...

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Bibliographic Details
Main Authors: Dante A. Suffredini, Hanish Sampath-Kumar, Yan Li, Lernik Ohanjanian, Kenneth E. Remy, Xizhong Cui, Peter Q. Eichacker
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Toxins
Subjects:
Bacillus anthracis
anthrax
lethal and edema toxins
cardiovascular dysfunction
shock
treatment
Online Access:http://www.mdpi.com/2072-6651/7/12/4891

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http://www.mdpi.com/2072-6651/7/12/4891

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