Multimodal Optical Medical Imaging Concepts Based on Optical Coherence Tomography
Optical medical imaging techniques in general exhibit outstanding resolution and molecule-specific contrast. They come however with a limited penetration in depth and small field of view. Multimodal concepts help to combine complementary strengths of different imaging technologies. The present artic...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-10-01
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| Series: | Frontiers in Physics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fphy.2018.00114/full |
| _version_ | 1817996333565345792 |
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| author | Rainer A. Leitgeb Rainer A. Leitgeb Bernhard Baumann |
| author_facet | Rainer A. Leitgeb Rainer A. Leitgeb Bernhard Baumann |
| author_sort | Rainer A. Leitgeb |
| collection | DOAJ |
| description | Optical medical imaging techniques in general exhibit outstanding resolution and molecule-specific contrast. They come however with a limited penetration in depth and small field of view. Multimodal concepts help to combine complementary strengths of different imaging technologies. The present article reviews the advantages of optical multimodal imaging concepts using optical coherence tomography (OCT) as core technology. In particular we first discuss polarization sensitive OCT, Doppler OCT and OCT angiography, OCT elastography, and spectroscopic OCT as intramodal concepts. To highlight intermodal imaging concepts, we then chose the combination of OCT with photoacoustics, and with non-linear optical microscopy. The selected multimodal concepts and their particular complementary strengths and applications are discussed in detail. The article concludes with notes on standardization of OCT imaging and multimodal extensions. |
| first_indexed | 2024-04-14T02:20:44Z |
| format | Article |
| id | doaj.art-4f98ebdb1e4143cca117a4c45a936823 |
| institution | Directory Open Access Journal |
| issn | 2296-424X |
| language | English |
| last_indexed | 2024-04-14T02:20:44Z |
| publishDate | 2018-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physics |
| spelling | doaj.art-4f98ebdb1e4143cca117a4c45a9368232022-12-22T02:18:03ZengFrontiers Media S.A.Frontiers in Physics2296-424X2018-10-01610.3389/fphy.2018.00114362487Multimodal Optical Medical Imaging Concepts Based on Optical Coherence TomographyRainer A. Leitgeb0Rainer A. Leitgeb1Bernhard Baumann2Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, AustriaChristian Doppler Laboratory for Innovative Optical Imaging and Its Translation to Medicine, Medical University of Vienna, Vienna, AustriaCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, AustriaOptical medical imaging techniques in general exhibit outstanding resolution and molecule-specific contrast. They come however with a limited penetration in depth and small field of view. Multimodal concepts help to combine complementary strengths of different imaging technologies. The present article reviews the advantages of optical multimodal imaging concepts using optical coherence tomography (OCT) as core technology. In particular we first discuss polarization sensitive OCT, Doppler OCT and OCT angiography, OCT elastography, and spectroscopic OCT as intramodal concepts. To highlight intermodal imaging concepts, we then chose the combination of OCT with photoacoustics, and with non-linear optical microscopy. The selected multimodal concepts and their particular complementary strengths and applications are discussed in detail. The article concludes with notes on standardization of OCT imaging and multimodal extensions.https://www.frontiersin.org/article/10.3389/fphy.2018.00114/fullmultimodal imagingvirtual biopsyoptical coherence tomographyDoppler OCTOCT angiographypolarization sensitive OCT |
| spellingShingle | Rainer A. Leitgeb Rainer A. Leitgeb Bernhard Baumann Multimodal Optical Medical Imaging Concepts Based on Optical Coherence Tomography Frontiers in Physics multimodal imaging virtual biopsy optical coherence tomography Doppler OCT OCT angiography polarization sensitive OCT |
| title | Multimodal Optical Medical Imaging Concepts Based on Optical Coherence Tomography |
| title_full | Multimodal Optical Medical Imaging Concepts Based on Optical Coherence Tomography |
| title_fullStr | Multimodal Optical Medical Imaging Concepts Based on Optical Coherence Tomography |
| title_full_unstemmed | Multimodal Optical Medical Imaging Concepts Based on Optical Coherence Tomography |
| title_short | Multimodal Optical Medical Imaging Concepts Based on Optical Coherence Tomography |
| title_sort | multimodal optical medical imaging concepts based on optical coherence tomography |
| topic | multimodal imaging virtual biopsy optical coherence tomography Doppler OCT OCT angiography polarization sensitive OCT |
| url | https://www.frontiersin.org/article/10.3389/fphy.2018.00114/full |
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