Anti-atherosclerosis effect of nobiletin via PINK1/Parkin-mediated mitophagy and NLRP3 inflammasome signaling pathway

Anti-atherosclerosis effect of nobiletin via PINK1/Parkin-mediated mitophagy and NLRP3 inflammasome signaling pathway

The incidence of atherosclerosis (AS) is enormously increased, which becomes a serious public health problem. Nobiletin (NOB), a natural active substance of citrus, is found possessed abundant nutritional activities. However, the mechanism of anti-atherosclerosis effect of NOB has not been elucidate...

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Bibliographic Details
Main Authors: Yudi Deng, Yali Tu, Xushan Yang, Xiaoshan Liao, Zijun Xia, Wenzhen Liao
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Journal of Functional Foods
Subjects:
Nobiletin
Anti-atherosclerosis effect
Mitophagy
NLRP3 inflammasome
Online Access:http://www.sciencedirect.com/science/article/pii/S175646462200439X

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