Research Progress of Targeted Therapy for Anaplastic Lymphoma Kinase and Other Rare Driver Genes in Advanced Non-small Cell Lung Cancer
Targeted therapy was one of the major treatments in advanced non-small cell lung cancer (NSCLC) with positive driver genes. This area of research progresses day by day, with novel target discoveries, novel drug development, and use of novel combination treatments. Researchers have also undergone dee...
Main Authors: | , |
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Format: | Article |
Language: | zho |
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Chinese Anti-Cancer Association; Chinese Antituberculosis Association
2017-01-01
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Series: | Chinese Journal of Lung Cancer |
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Online Access: | http://dx.doi.org/10.3779/j.issn.1009-3419.2017.01.10 |
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author | Quan ZHANG Shucai ZHANG |
author_facet | Quan ZHANG Shucai ZHANG |
author_sort | Quan ZHANG |
collection | DOAJ |
description | Targeted therapy was one of the major treatments in advanced non-small cell lung cancer (NSCLC) with positive driver genes. This area of research progresses day by day, with novel target discoveries, novel drug development, and use of novel combination treatments. Researchers have also undergone deep investigation about the molecular mechanisms underlying inherent or acquired resistance to these targeted therapies. This review aimed to summarize the advanced developments of targeted therapy for anaplastic lymphoma kinase (ALK) and other rare driver genes in NSCLC. |
first_indexed | 2024-04-12T13:37:25Z |
format | Article |
id | doaj.art-4f9c899ead3c44c1a84fe36188ba766a |
institution | Directory Open Access Journal |
issn | 1009-3419 1999-6187 |
language | zho |
last_indexed | 2024-04-12T13:37:25Z |
publishDate | 2017-01-01 |
publisher | Chinese Anti-Cancer Association; Chinese Antituberculosis Association |
record_format | Article |
series | Chinese Journal of Lung Cancer |
spelling | doaj.art-4f9c899ead3c44c1a84fe36188ba766a2022-12-22T03:30:58ZzhoChinese Anti-Cancer Association; Chinese Antituberculosis AssociationChinese Journal of Lung Cancer1009-34191999-61872017-01-01201667210.3779/j.issn.1009-3419.2017.01.10Research Progress of Targeted Therapy for Anaplastic Lymphoma Kinase and Other Rare Driver Genes in Advanced Non-small Cell Lung CancerQuan ZHANG0Shucai ZHANG1Department of Medical Oncology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor
Research Institute, Beijing 101149, ChinaDepartment of Medical Oncology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor
Research Institute, Beijing 101149, ChinaTargeted therapy was one of the major treatments in advanced non-small cell lung cancer (NSCLC) with positive driver genes. This area of research progresses day by day, with novel target discoveries, novel drug development, and use of novel combination treatments. Researchers have also undergone deep investigation about the molecular mechanisms underlying inherent or acquired resistance to these targeted therapies. This review aimed to summarize the advanced developments of targeted therapy for anaplastic lymphoma kinase (ALK) and other rare driver genes in NSCLC.http://dx.doi.org/10.3779/j.issn.1009-3419.2017.01.10Lung neoplasmsTargeted therapyALK |
spellingShingle | Quan ZHANG Shucai ZHANG Research Progress of Targeted Therapy for Anaplastic Lymphoma Kinase and Other Rare Driver Genes in Advanced Non-small Cell Lung Cancer Chinese Journal of Lung Cancer Lung neoplasms Targeted therapy ALK |
title | Research Progress of Targeted Therapy for Anaplastic Lymphoma Kinase and Other Rare Driver Genes in Advanced Non-small Cell Lung Cancer |
title_full | Research Progress of Targeted Therapy for Anaplastic Lymphoma Kinase and Other Rare Driver Genes in Advanced Non-small Cell Lung Cancer |
title_fullStr | Research Progress of Targeted Therapy for Anaplastic Lymphoma Kinase and Other Rare Driver Genes in Advanced Non-small Cell Lung Cancer |
title_full_unstemmed | Research Progress of Targeted Therapy for Anaplastic Lymphoma Kinase and Other Rare Driver Genes in Advanced Non-small Cell Lung Cancer |
title_short | Research Progress of Targeted Therapy for Anaplastic Lymphoma Kinase and Other Rare Driver Genes in Advanced Non-small Cell Lung Cancer |
title_sort | research progress of targeted therapy for anaplastic lymphoma kinase and other rare driver genes in advanced non small cell lung cancer |
topic | Lung neoplasms Targeted therapy ALK |
url | http://dx.doi.org/10.3779/j.issn.1009-3419.2017.01.10 |
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