Identification of potential target genes of honokiol in overcoming breast cancer resistance to tamoxifen

Identification of potential target genes of honokiol in overcoming breast cancer resistance to tamoxifen

BackgroundHonokiol (HON) inhibits epidermal growth factor receptor (EGFR) signaling and increases the activity of erlotinib, an EGFR inhibitor, in human head and neck cancers. In this study, using a bioinformatics approach and in vitro experiments, we assessed the target genes of HON against breast...

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Bibliographic Details
Main Authors: Adam Hermawan, Herwandhani Putri, Naufa Hanif, Nurul Fatimah, Heri Himawan Prasetio
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Oncology
Subjects:
honokiol
tamoxifen resistance
breast cancer
bioinformatics
targeted therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1019025/full

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