Structural insights into Cas9 mismatch: promising for development of high-fidelity Cas9 variants
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2022-08-01
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| Series: | Signal Transduction and Targeted Therapy |
| Online Access: | https://doi.org/10.1038/s41392-022-01139-z |
| _version_ | 1811342705856348160 |
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| author | Honghai Tang Daqi Wang Yilai Shu |
| author_facet | Honghai Tang Daqi Wang Yilai Shu |
| author_sort | Honghai Tang |
| collection | DOAJ |
| first_indexed | 2024-04-13T19:16:43Z |
| format | Article |
| id | doaj.art-4f9d613a22d54de4afa10b3de41a83d6 |
| institution | Directory Open Access Journal |
| issn | 2059-3635 |
| language | English |
| last_indexed | 2024-04-13T19:16:43Z |
| publishDate | 2022-08-01 |
| publisher | Nature Publishing Group |
| record_format | Article |
| series | Signal Transduction and Targeted Therapy |
| spelling | doaj.art-4f9d613a22d54de4afa10b3de41a83d62022-12-22T02:33:40ZengNature Publishing GroupSignal Transduction and Targeted Therapy2059-36352022-08-01711310.1038/s41392-022-01139-zStructural insights into Cas9 mismatch: promising for development of high-fidelity Cas9 variantsHonghai Tang0Daqi Wang1Yilai Shu2ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan UniversityENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan UniversityENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan Universityhttps://doi.org/10.1038/s41392-022-01139-z |
| spellingShingle | Honghai Tang Daqi Wang Yilai Shu Structural insights into Cas9 mismatch: promising for development of high-fidelity Cas9 variants Signal Transduction and Targeted Therapy |
| title | Structural insights into Cas9 mismatch: promising for development of high-fidelity Cas9 variants |
| title_full | Structural insights into Cas9 mismatch: promising for development of high-fidelity Cas9 variants |
| title_fullStr | Structural insights into Cas9 mismatch: promising for development of high-fidelity Cas9 variants |
| title_full_unstemmed | Structural insights into Cas9 mismatch: promising for development of high-fidelity Cas9 variants |
| title_short | Structural insights into Cas9 mismatch: promising for development of high-fidelity Cas9 variants |
| title_sort | structural insights into cas9 mismatch promising for development of high fidelity cas9 variants |
| url | https://doi.org/10.1038/s41392-022-01139-z |
| work_keys_str_mv | AT honghaitang structuralinsightsintocas9mismatchpromisingfordevelopmentofhighfidelitycas9variants AT daqiwang structuralinsightsintocas9mismatchpromisingfordevelopmentofhighfidelitycas9variants AT yilaishu structuralinsightsintocas9mismatchpromisingfordevelopmentofhighfidelitycas9variants |