Severe lymphopenia as a prognostic factor in rectal cancer patients receiving adjuvant chemoradiotherapy: a retrospective study

Severe lymphopenia as a prognostic factor in rectal cancer patients receiving adjuvant chemoradiotherapy: a retrospective study

Abstract The relationship between total lymphocyte counts (TLCs) and survival is not well documented in rectal cancer. This study aimed to investigate the association between TLCs and disease-free survival (DFS) and identify factors associated with lymphopenia in locally advanced rectal cancer patie...

Full description

Bibliographic Details
Main Authors:	Shuang Li, Weiping Yao, Ruiqi Liu, Yanwei Lu, Haibo Zhang, Xiaodong Liang
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-05-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-023-34145-4

Similar Items

Post-chemoradiotherapy adjuvant chemotherapy of rectal cancer
by: E. V. Ledin, et al.
Published: (2018-08-01)

ADJUVANT CHEMOTHERAPY AFTER RECTAL CANCER CHEMORADIOTHERAPY
by: M. Yu. Fedyanin, et al.
Published: (2015-02-01)

Role of adjuvant chemotherapy in patients with rectal cancer after preoperative chemoradiotherapy: results of a retrospective study
by: M. Yu. Fedyanin, et al.
Published: (2018-07-01)

Impact of Lymphopenia Recovery After Chemoradiotherapy on Durvalumab Consolidation Therapy in Stage III NSCLC
by: Tomoki Kuge, MD, et al.
Published: (2023-05-01)

Neoadjuvant chemoradiotherapy induced lymphopenia in gastric cancer and associations with spleen dosimetry and survival outcomes
by: Ji-jin Wang, et al.
Published: (2023-05-01)

Poor prognostic and staging value of tumor deposit in locally advanced rectal cancer with neoadjuvant chemoradiotherapy
by: Yaqi Wang, et al.
Published: (2019-04-01)

Prognostic Value and Risk Factors of Treatment-Related Lymphopenia in Malignant Glioma Patients Treated With Chemoradiotherapy: A Systematic Review and Meta-Analysis
by: Yongchao Zhang, et al.
Published: (2022-01-01)

Possible Mechanisms of Lymphopenia in Severe Tuberculosis
by: Fei Li, et al.
Published: (2023-10-01)

Lymphopenia, Lymphopenia-Induced Proliferation, and Autoimmunity
by: Ting-Ting Sheu, et al.
Published: (2021-04-01)

Retrospective cohort study for thrombocytopenia during concurrent chemoradiotherapy for rectal cancer
by: Yue Teng, et al.
Published: (2024-01-01)

Pericardial irradiation dose may be strongly associated with grade 4 lymphopenia and affect prognosis in patients with locally advanced esophageal cancer receiving definitive concurrent chemoradiotherapy
by: Xianyan Chen, et al.
Published: (2023-09-01)

Targeted Next-Generation Sequencing-Based Multiple Gene Mutation Profiling of Patients with Rectal Adenocarcinoma Receiving or Not Receiving Neoadjuvant Chemoradiotherapy
by: You-Kang Chang, et al.
Published: (2022-09-01)

Utility of RGNEF in the Prediction of Clinical Prognosis in Patients with Rectal Cancer Receiving Preoperative Concurrent Chemoradiotherapy
by: Chih-I. Chen, et al.
Published: (2021-12-01)

Genetic polymorphisms in genes regulating cell death and prognosis of patients with rectal cancer receiving postoperative chemoradiotherapy
by: Hongxia Chen, et al.
Published: (2023-04-01)

The role of adjuvant chemotherapy in rectal cancer patients with ypT0-2N0 after neoadjuvant chemoradiotherapy
by: Jianguo Yang, et al.
Published: (2024-02-01)

Severe radiation-induced lymphopenia during concurrent chemoradiotherapy for stage III non-small cell lung cancer: external validation of two prediction models
by: Peter S. N. van Rossum, et al.
Published: (2023-11-01)

Lymphopenia in diverticulitis.
by: Baker, SR, et al.
Published: (1991)

Prognostic and Predictive Biomarkers in Patients with Locally Advanced Rectal Cancer (LARC) Treated with Preoperative Chemoradiotherapy
by: Alfonso Martín-Carnicero, et al.
Published: (2022-10-01)

Splenic irradiation contributes to grade ≥ 3 lymphopenia after adjuvant chemoradiation for stomach cancer
by: Shing Fung Lee, et al.
Published: (2022-09-01)

Effect of Lymphopenia on Tumor Response and Clinical Outcomes Following Chemoradiotherapy in Stage III Non-Small Cell Lung Cancer
by: Deck J, et al.
Published: (2023-05-01)

Biomarkers of Favorable vs. Unfavorable Responses in Locally Advanced Rectal Cancer Patients Receiving Neoadjuvant Concurrent Chemoradiotherapy
by: Hsin-Hua Lee, et al.
Published: (2022-05-01)

Oral fluorpyrimidines in preoperative chemoradiotherapy for operable rectal cancer
by: Yu. A. Barsukov, et al.
Published: (2016-01-01)

BIOLOGICAL MARKERS OF RECTAL CANCER NEOADJUVANT CHEMORADIOTHERAPY EFFICACY
by: M. Yu. Fedyanin, et al.
Published: (2015-02-01)

Neoadjuvant chemoradiotherapy in combined treatment of patients with rectal cancer
by: N. A. Maistrenko, et al.
Published: (2017-08-01)

LYMPHOPENIA: THE MAIN CAUSES
by: N. T. Vatutin, et al.
Published: (2016-05-01)

Radiomics of skeletal muscle helps to predict gastrointestinal toxicity in locally advanced rectal cancer patients receiving neoadjuvant chemoradiotherapy
by: Wang Yang, et al.
Published: (2024-01-01)

An immune-related gene prognostic prediction risk model for neoadjuvant chemoradiotherapy in rectal cancer using artificial intelligence
by: Pei Shu, et al.
Published: (2024-02-01)

Platelet-to-albumin ratio and radiation-induced lymphopenia—prognostic biomarker for carcinoma esophagus
by: Adrija Ghosh, et al.
Published: (2024-02-01)

Prognostic impact of radiotherapy-induced-lymphopenia in patients treated with breast-conservative surgery
by: Chang Ik Yoon, et al.
Published: (2023-09-01)

The roles, molecular interactions, and therapeutic value of CDK16 in human cancers
by: Xiao Wang, et al.
Published: (2023-08-01)

Lymphopenia: A predictive marker of disease severity in COVID-19 infection
by: Georgeta Daniela Georgescu, et al.
Published: (2021-12-01)

Severe Lymphopenia as a Predictor of COVID-19 Mortality in Immunosuppressed Patients
by: María Martínez-Urbistondo, et al.
Published: (2021-08-01)

Use of patient‐derived tumor organoid platform to predict the benefit of postoperative adjuvant chemotherapy for poor responders to neoadjuvant chemoradiotherapy in locally advanced rectal cancer
by: Weisong Xue, et al.
Published: (2023-11-01)

Rectal adenocarcinoma with oncocytic features: possible relationship with preoperative chemoradiotherapy.
by: Rouzbahman, M, et al.
Published: (2006)

The role of chemoradiotherapy in the treatment of neuroendocrine rectal cancer: case reports
by: S. S. Gordeev, et al.
Published: (2022-09-01)

Organ preservation for early rectal cancer using preoperative chemoradiotherapy
by: Gyung Mo Son
Published: (2023-06-01)

The modified Glasgow prognostic score is a reliable predictor of oncological outcomes in patients with rectal cancer undergoing neoadjuvant chemoradiotherapy
by: Atsushi Shimada, et al.
Published: (2023-10-01)

A retrospective cohort study of neoadjuvant chemoradiotherapy combined with immune checkpoint inhibitors in locally advanced rectal cancer
by: Zhuo Chen, et al.
Published: (2024-06-01)

Impact of glucocorticoids on the efficacy of neoadjuvant chemoradiotherapy and survival of patients with locally advanced rectal cancer: a retrospective study
by: Xiaoxue Huang, et al.
Published: (2023-03-01)

Prognostic Value of Neutrophils-to-Lymphocytes Ratio and Platelets-to-Lymphocytes Ratio in Sepsis Patients With Lymphopenia
by: Xianming Qiu, et al.
Published: (2024-01-01)