Spectrum of radiological presentations among the patients of intracranial metastasis
Background: Brain metastasis has been the most common primary intracranial space occupying lesion (ICSOL) in adult patients.The main systemic malignancies presenting with high tendency to invade brain parenchyma are –lung, breast, melanoma, renal and colon cancers etc. Aims and Objectives: To...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Manipal College of Medical Sciences, Pokhara
2019-07-01
|
| Series: | Asian Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/23781 |
| _version_ | 1818973642908762112 |
|---|---|
| author | Shilpi Muchhoria Sourabh Dixit BV Sandeep Suniti Kumar Saha Abhishek Nadkarni Debjyoti Pathak |
| author_facet | Shilpi Muchhoria Sourabh Dixit BV Sandeep Suniti Kumar Saha Abhishek Nadkarni Debjyoti Pathak |
| author_sort | Shilpi Muchhoria |
| collection | DOAJ |
| description | Background: Brain metastasis has been the most common primary intracranial space occupying lesion (ICSOL) in adult patients.The main systemic malignancies presenting with high tendency to invade brain parenchyma are –lung, breast, melanoma, renal and colon cancers etc.
Aims and Objectives:
To study the various radiological presentations in cases of intracranial metatstasis.
To assess the radiological presentations to differentiate metastasis from other differential diagnosis.
Materials and Methods: The present cross sectional study was carried out amongst 32 patients who had been visited tertiary care hospital in Kolkata with radiological features and histopathology suggestive of metastatic lesion.
Results: The mean age of the subjects was 46.56 years and the maximum number of cases presented in 5th and 6th decades of life. CT Scan showed 75% patient had metastatic lesion appearing hyperdense on plain study and 25% had lesion hypodense on plain CT Scan. On T1 weighted images- In 75% of patient the metastatic lesions were hypointense to brain parenchyma and in 12.5% they were isointense and 12.5% they were hyperintense.T2 weighted images- In 62.5% of patient the metastatic lesions were hyperintense to brain parenchyma and in 25% patients they were isointense and in 12.5% they were hypointense. Contrast Images – 37.5% of patients had homogenous enhancement and 50% had heterogeneous enhancement and 12.5% had ring shaped enhancement. In Biopsy about 75% the metastatic lesion turned out to be metastatic carcinoma.
Conclusion: A thorough and systematic approach to radiological investigation is crucial for proper identification of intracranial metastatic lesions. |
| first_indexed | 2024-12-20T15:27:25Z |
| format | Article |
| id | doaj.art-4fb01e8b4a4e4a42b5c6b37a473e9c6c |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-12-20T15:27:25Z |
| publishDate | 2019-07-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-4fb01e8b4a4e4a42b5c6b37a473e9c6c2022-12-21T19:35:46ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762019-07-011043238https://doi.org/10.3126/ajms.v10i4.23781Spectrum of radiological presentations among the patients of intracranial metastasisShilpi Muchhoria 0Sourabh Dixit 1BV Sandeep2Suniti Kumar Saha 3Abhishek Nadkarni 4Debjyoti Pathak 5Bhopal Memorial Hospital and Research Centre (BMHRC) Bhopal, Madhya Pradesh, India https://orcid.org/0000-0001-5000-5772Bhopal Memorial Hospital and Research Centre (BMHRC) Bhopal, Madhya Pradesh, India http://orcid.org/0000-0003-1085-7000Vydehi Medical College, Karnataka Bengaluru, India https://orcid.org/0000-0003-4248-9062Nil Ratan Sircar Medical college and Hospital, Kolkata, West Bengal, India https://orcid.org/0000-0002-6217-9355Nil Ratan Sircar Medical college and Hospital, Kolkata, West Bengal, India https://orcid.org/0000-0003-2842-4756Nil Ratan Sircar Medical college and Hospital, Kolkata, West Bengal, India https://orcid.org/0000-0002-8503-4618Background: Brain metastasis has been the most common primary intracranial space occupying lesion (ICSOL) in adult patients.The main systemic malignancies presenting with high tendency to invade brain parenchyma are –lung, breast, melanoma, renal and colon cancers etc. Aims and Objectives: To study the various radiological presentations in cases of intracranial metatstasis. To assess the radiological presentations to differentiate metastasis from other differential diagnosis. Materials and Methods: The present cross sectional study was carried out amongst 32 patients who had been visited tertiary care hospital in Kolkata with radiological features and histopathology suggestive of metastatic lesion. Results: The mean age of the subjects was 46.56 years and the maximum number of cases presented in 5th and 6th decades of life. CT Scan showed 75% patient had metastatic lesion appearing hyperdense on plain study and 25% had lesion hypodense on plain CT Scan. On T1 weighted images- In 75% of patient the metastatic lesions were hypointense to brain parenchyma and in 12.5% they were isointense and 12.5% they were hyperintense.T2 weighted images- In 62.5% of patient the metastatic lesions were hyperintense to brain parenchyma and in 25% patients they were isointense and in 12.5% they were hypointense. Contrast Images – 37.5% of patients had homogenous enhancement and 50% had heterogeneous enhancement and 12.5% had ring shaped enhancement. In Biopsy about 75% the metastatic lesion turned out to be metastatic carcinoma. Conclusion: A thorough and systematic approach to radiological investigation is crucial for proper identification of intracranial metastatic lesions.https://www.nepjol.info/index.php/AJMS/article/view/23781melanomaintracranial metastasiscarcinomaintracranial space occupying lesion |
| spellingShingle | Shilpi Muchhoria Sourabh Dixit BV Sandeep Suniti Kumar Saha Abhishek Nadkarni Debjyoti Pathak Spectrum of radiological presentations among the patients of intracranial metastasis Asian Journal of Medical Sciences melanoma intracranial metastasis carcinoma intracranial space occupying lesion |
| title | Spectrum of radiological presentations among the patients of intracranial metastasis |
| title_full | Spectrum of radiological presentations among the patients of intracranial metastasis |
| title_fullStr | Spectrum of radiological presentations among the patients of intracranial metastasis |
| title_full_unstemmed | Spectrum of radiological presentations among the patients of intracranial metastasis |
| title_short | Spectrum of radiological presentations among the patients of intracranial metastasis |
| title_sort | spectrum of radiological presentations among the patients of intracranial metastasis |
| topic | melanoma intracranial metastasis carcinoma intracranial space occupying lesion |
| url | https://www.nepjol.info/index.php/AJMS/article/view/23781 |
| work_keys_str_mv | AT shilpimuchhoria spectrumofradiologicalpresentationsamongthepatientsofintracranialmetastasis AT sourabhdixit spectrumofradiologicalpresentationsamongthepatientsofintracranialmetastasis AT bvsandeep spectrumofradiologicalpresentationsamongthepatientsofintracranialmetastasis AT sunitikumarsaha spectrumofradiologicalpresentationsamongthepatientsofintracranialmetastasis AT abhisheknadkarni spectrumofradiologicalpresentationsamongthepatientsofintracranialmetastasis AT debjyotipathak spectrumofradiologicalpresentationsamongthepatientsofintracranialmetastasis |