The Role of Multimodality Imaging for Percutaneous Coronary Intervention in Patients With Chronic Total Occlusions

BackgroundPercutaneous coronary intervention (PCI) of Chronic total occlusions (CTOs) has been traditionally considered a challenging procedure, with a lower success rate and a higher incidence of complications compared to non-CTO-PCI. An accurate and comprehensive evaluation of potential candidates...

Full description

Bibliographic Details
Main Authors: Eleonora Melotti, Marta Belmonte, Carlo Gigante, Vincenzo Mallia, Saima Mushtaq, Edoardo Conte, Danilo Neglia, Gianluca Pontone, Carlos Collet, Jeroen Sonck, Luca Grancini, Antonio L. Bartorelli, Daniele Andreini
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.823091/full
_version_ 1818007505559617536
author Eleonora Melotti
Marta Belmonte
Carlo Gigante
Vincenzo Mallia
Saima Mushtaq
Edoardo Conte
Danilo Neglia
Danilo Neglia
Gianluca Pontone
Carlos Collet
Jeroen Sonck
Jeroen Sonck
Luca Grancini
Antonio L. Bartorelli
Antonio L. Bartorelli
Daniele Andreini
Daniele Andreini
author_facet Eleonora Melotti
Marta Belmonte
Carlo Gigante
Vincenzo Mallia
Saima Mushtaq
Edoardo Conte
Danilo Neglia
Danilo Neglia
Gianluca Pontone
Carlos Collet
Jeroen Sonck
Jeroen Sonck
Luca Grancini
Antonio L. Bartorelli
Antonio L. Bartorelli
Daniele Andreini
Daniele Andreini
author_sort Eleonora Melotti
collection DOAJ
description BackgroundPercutaneous coronary intervention (PCI) of Chronic total occlusions (CTOs) has been traditionally considered a challenging procedure, with a lower success rate and a higher incidence of complications compared to non-CTO-PCI. An accurate and comprehensive evaluation of potential candidates for CTO-PCI is of great importance. Indeed, assessment of myocardial viability, left ventricular function, individual risk profile and coronary lesion complexity as well as detection of inducible ischemia are key information that should be integrated for a shared treatment decision and interventional strategy planning. In this regard, multimodality imaging can provide combined data that can be very useful for the decision-making algorithm and for planning percutaneous CTO recanalization.AimsThe purpose of this article is to appraise the value and limitations of several non-invasive imaging tools to provide relevant information about the anatomical characteristics and functional impact of CTOs that may be useful for the pre-procedural assessment and follow-up of candidates for CTO-PCI. They include echocardiography, coronary computed tomography angiography (CCTA), nuclear imaging, and cardiac magnetic resonance (CMR). As an example, CCTA can accurately delineate CTO location and length, distal coronary bed, vessel tortuosity and calcifications that can predict PCI success, whereas stress CMR, nuclear imaging and stress-CT can provide functional evaluation in terms of myocardial ischemia and viability and perfusion defect extension.
first_indexed 2024-04-14T05:17:29Z
format Article
id doaj.art-4fb11d1076e24527b7d1bae472a0956c
institution Directory Open Access Journal
issn 2297-055X
language English
last_indexed 2024-04-14T05:17:29Z
publishDate 2022-05-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Cardiovascular Medicine
spelling doaj.art-4fb11d1076e24527b7d1bae472a0956c2022-12-22T02:10:20ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-05-01910.3389/fcvm.2022.823091823091The Role of Multimodality Imaging for Percutaneous Coronary Intervention in Patients With Chronic Total OcclusionsEleonora Melotti0Marta Belmonte1Carlo Gigante2Vincenzo Mallia3Saima Mushtaq4Edoardo Conte5Danilo Neglia6Danilo Neglia7Gianluca Pontone8Carlos Collet9Jeroen Sonck10Jeroen Sonck11Luca Grancini12Antonio L. Bartorelli13Antonio L. Bartorelli14Daniele Andreini15Daniele Andreini16Centro Cardiologico Monzino, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS), Milan, ItalyCentro Cardiologico Monzino, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS), Milan, ItalyCentro Cardiologico Monzino, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS), Milan, ItalyCentro Cardiologico Monzino, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS), Milan, ItalyCentro Cardiologico Monzino, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS), Milan, ItalyCentro Cardiologico Monzino, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS), Milan, ItalyFondazione Toscana G. Monasterio, Pisa, ItalyIstituto di Scienze della Vita Scuola Superiore Sant'Anna, Pisa, ItalyCentro Cardiologico Monzino, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS), Milan, ItalyCardiovascular Center Aalst, OLV-Clinic, Aalst, BelgiumCardiovascular Center Aalst, OLV-Clinic, Aalst, BelgiumDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, ItalyCentro Cardiologico Monzino, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS), Milan, ItalyCentro Cardiologico Monzino, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS), Milan, ItalyDepartment of Biomedical and Clinical Sciences “Luigi Sacco”, University of Milan, Milan, ItalyCentro Cardiologico Monzino, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS), Milan, ItalyDepartment of Biomedical and Clinical Sciences “Luigi Sacco”, University of Milan, Milan, ItalyBackgroundPercutaneous coronary intervention (PCI) of Chronic total occlusions (CTOs) has been traditionally considered a challenging procedure, with a lower success rate and a higher incidence of complications compared to non-CTO-PCI. An accurate and comprehensive evaluation of potential candidates for CTO-PCI is of great importance. Indeed, assessment of myocardial viability, left ventricular function, individual risk profile and coronary lesion complexity as well as detection of inducible ischemia are key information that should be integrated for a shared treatment decision and interventional strategy planning. In this regard, multimodality imaging can provide combined data that can be very useful for the decision-making algorithm and for planning percutaneous CTO recanalization.AimsThe purpose of this article is to appraise the value and limitations of several non-invasive imaging tools to provide relevant information about the anatomical characteristics and functional impact of CTOs that may be useful for the pre-procedural assessment and follow-up of candidates for CTO-PCI. They include echocardiography, coronary computed tomography angiography (CCTA), nuclear imaging, and cardiac magnetic resonance (CMR). As an example, CCTA can accurately delineate CTO location and length, distal coronary bed, vessel tortuosity and calcifications that can predict PCI success, whereas stress CMR, nuclear imaging and stress-CT can provide functional evaluation in terms of myocardial ischemia and viability and perfusion defect extension.https://www.frontiersin.org/articles/10.3389/fcvm.2022.823091/fullmultimodality imagingchronic total occlusion (CTO)cardiac CTcardiac magnetic resonancesingle photon emission computed tomography (SPECT)echocardiography
spellingShingle Eleonora Melotti
Marta Belmonte
Carlo Gigante
Vincenzo Mallia
Saima Mushtaq
Edoardo Conte
Danilo Neglia
Danilo Neglia
Gianluca Pontone
Carlos Collet
Jeroen Sonck
Jeroen Sonck
Luca Grancini
Antonio L. Bartorelli
Antonio L. Bartorelli
Daniele Andreini
Daniele Andreini
The Role of Multimodality Imaging for Percutaneous Coronary Intervention in Patients With Chronic Total Occlusions
Frontiers in Cardiovascular Medicine
multimodality imaging
chronic total occlusion (CTO)
cardiac CT
cardiac magnetic resonance
single photon emission computed tomography (SPECT)
echocardiography
title The Role of Multimodality Imaging for Percutaneous Coronary Intervention in Patients With Chronic Total Occlusions
title_full The Role of Multimodality Imaging for Percutaneous Coronary Intervention in Patients With Chronic Total Occlusions
title_fullStr The Role of Multimodality Imaging for Percutaneous Coronary Intervention in Patients With Chronic Total Occlusions
title_full_unstemmed The Role of Multimodality Imaging for Percutaneous Coronary Intervention in Patients With Chronic Total Occlusions
title_short The Role of Multimodality Imaging for Percutaneous Coronary Intervention in Patients With Chronic Total Occlusions
title_sort role of multimodality imaging for percutaneous coronary intervention in patients with chronic total occlusions
topic multimodality imaging
chronic total occlusion (CTO)
cardiac CT
cardiac magnetic resonance
single photon emission computed tomography (SPECT)
echocardiography
url https://www.frontiersin.org/articles/10.3389/fcvm.2022.823091/full
work_keys_str_mv AT eleonoramelotti theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT martabelmonte theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT carlogigante theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT vincenzomallia theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT saimamushtaq theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT edoardoconte theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT daniloneglia theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT daniloneglia theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT gianlucapontone theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT carloscollet theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT jeroensonck theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT jeroensonck theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT lucagrancini theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT antoniolbartorelli theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT antoniolbartorelli theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT danieleandreini theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT danieleandreini theroleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT eleonoramelotti roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT martabelmonte roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT carlogigante roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT vincenzomallia roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT saimamushtaq roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT edoardoconte roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT daniloneglia roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT daniloneglia roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT gianlucapontone roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT carloscollet roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT jeroensonck roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT jeroensonck roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT lucagrancini roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT antoniolbartorelli roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT antoniolbartorelli roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT danieleandreini roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions
AT danieleandreini roleofmultimodalityimagingforpercutaneouscoronaryinterventioninpatientswithchronictotalocclusions