The Effect of Ethambutol on Optic Nerve by Spectral Domain Optical Coherence Tomography
Aim:To evaluate; the retinal nerve fiber layer difference between healthy control groups and patients who were taking ethambutol medication by using spectral domain optical coherence tomography (SD-OCT) and to evaluate the usage of SD-OCT for early diagnosis of optic neuropathy due to ethambutol.Mat...
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| Format: | Article |
| Language: | English |
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Galenos Yayincilik
2020-04-01
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| Series: | Namık Kemal Tıp Dergisi |
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http://namikkemalmedj.com/archives/archive-detail/article-preview/the-effect-of-ethambutol-on-optic-nerve-by-spectra/40340
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| _version_ | 1828015889214078976 |
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| author | Gül VARAN Ahmet ŞAHİN |
| author_facet | Gül VARAN Ahmet ŞAHİN |
| author_sort | Gül VARAN |
| collection | DOAJ |
| description | Aim:To evaluate; the retinal nerve fiber layer difference between healthy control groups and patients who were taking ethambutol medication by using spectral domain optical coherence tomography (SD-OCT) and to evaluate the usage of SD-OCT for early diagnosis of optic neuropathy due to ethambutol.Materials and Methods:40 eyes of 20 patients using ethambutol for at least 2 months have been compared to 40 eyes of 20 healthy subjects of the same age and sex in terms of RNFL thickness parameters. All participants underwent a complete ophthalmologic examination. Patients with a history of disease or drug use affecting RNFL were not included in the study. Superior, inferior, nasal and temporal quadrants and macular thickness were evaluated in SD-OCT.Results:RNFL thickness values of ethambutol patients were as follows: superior 123,12±16,07μm, inferior 131,20±13,26 μm, nazal 79,47±11,54 μm, temporal 78,80±12,82 μm, macular thickness 266,16±11,94 μm.Conclusion:There was statistically significant increase in temporal quadrant and decrease in nasal quadrant in patients taking ethambutol medication compared to control group (p<0,05). There was no statistically significant change in superior and inferior quadrant and macular thickness (p>0,05). |
| first_indexed | 2024-04-10T10:26:33Z |
| format | Article |
| id | doaj.art-4fb406bdd8ff4d80aa31b40a0700f6db |
| institution | Directory Open Access Journal |
| issn | 2587-0262 |
| language | English |
| last_indexed | 2024-04-10T10:26:33Z |
| publishDate | 2020-04-01 |
| publisher | Galenos Yayincilik |
| record_format | Article |
| series | Namık Kemal Tıp Dergisi |
| spelling | doaj.art-4fb406bdd8ff4d80aa31b40a0700f6db2023-02-15T16:21:22ZengGalenos YayincilikNamık Kemal Tıp Dergisi2587-02622020-04-0181434710.37696/nkmj.66077913049054The Effect of Ethambutol on Optic Nerve by Spectral Domain Optical Coherence TomographyGül VARAN0Ahmet ŞAHİN1 Çorlu Devlet Hastanesi, Tekirdağ, TÜRKİYE Kepez Devlet Hastanesi, Antalya, TÜRKİYE Aim:To evaluate; the retinal nerve fiber layer difference between healthy control groups and patients who were taking ethambutol medication by using spectral domain optical coherence tomography (SD-OCT) and to evaluate the usage of SD-OCT for early diagnosis of optic neuropathy due to ethambutol.Materials and Methods:40 eyes of 20 patients using ethambutol for at least 2 months have been compared to 40 eyes of 20 healthy subjects of the same age and sex in terms of RNFL thickness parameters. All participants underwent a complete ophthalmologic examination. Patients with a history of disease or drug use affecting RNFL were not included in the study. Superior, inferior, nasal and temporal quadrants and macular thickness were evaluated in SD-OCT.Results:RNFL thickness values of ethambutol patients were as follows: superior 123,12±16,07μm, inferior 131,20±13,26 μm, nazal 79,47±11,54 μm, temporal 78,80±12,82 μm, macular thickness 266,16±11,94 μm.Conclusion:There was statistically significant increase in temporal quadrant and decrease in nasal quadrant in patients taking ethambutol medication compared to control group (p<0,05). There was no statistically significant change in superior and inferior quadrant and macular thickness (p>0,05). http://namikkemalmedj.com/archives/archive-detail/article-preview/the-effect-of-ethambutol-on-optic-nerve-by-spectra/40340 ethambutoloptic neuropathysd-octtuberculosis treatment |
| spellingShingle | Gül VARAN Ahmet ŞAHİN The Effect of Ethambutol on Optic Nerve by Spectral Domain Optical Coherence Tomography Namık Kemal Tıp Dergisi ethambutol optic neuropathy sd-oct tuberculosis treatment |
| title | The Effect of Ethambutol on Optic Nerve by Spectral Domain Optical Coherence Tomography |
| title_full | The Effect of Ethambutol on Optic Nerve by Spectral Domain Optical Coherence Tomography |
| title_fullStr | The Effect of Ethambutol on Optic Nerve by Spectral Domain Optical Coherence Tomography |
| title_full_unstemmed | The Effect of Ethambutol on Optic Nerve by Spectral Domain Optical Coherence Tomography |
| title_short | The Effect of Ethambutol on Optic Nerve by Spectral Domain Optical Coherence Tomography |
| title_sort | effect of ethambutol on optic nerve by spectral domain optical coherence tomography |
| topic | ethambutol optic neuropathy sd-oct tuberculosis treatment |
| url |
http://namikkemalmedj.com/archives/archive-detail/article-preview/the-effect-of-ethambutol-on-optic-nerve-by-spectra/40340
|
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