Reactive oxygen species oxidize STING and suppress interferon production

Reactive oxygen species oxidize STING and suppress interferon production

Reactive oxygen species (ROS) are by-products of cellular respiration that can promote oxidative stress and damage cellular proteins and lipids. One canonical role of ROS is to defend the cell against invading bacterial and viral pathogens. Curiously, some viruses, including herpesviruses, thrive de...

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Bibliographic Details
Main Authors: Lili Tao, Andrew Lemoff, Guoxun Wang, Christina Zarek, Alexandria Lowe, Nan Yan, Tiffany A Reese
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-09-01
Series:eLife
Subjects:
reactive oxygen species
STING
herpesvirus
interferon
redox regulation
Online Access:https://elifesciences.org/articles/57837

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