2D DIGE proteomic analysis highlights delayed postnatal repression of α‐fetoprotein expression in homocystinuria model mice

Cystathionine β‐synthase‐deficient (Cbs−/−) mice, an animal model for homocystinuria, exhibit hepatic steatosis and juvenile semilethality via as yet unknown mechanisms. The plasma protein profile ofCbs−/− mice was investigated by proteomic analysis using two‐dimensional difference gel electrophores...

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Bibliographic Details
Main Authors: Shotaro Kamata, Noriyuki Akahoshi, Isao Ishii
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1016/j.fob.2015.06.008