Prevalence of Onychomycosis in the Psoriatic Patients in a Tertiary Care Hospital, Chennai, Tamil Nadu, India
Introduction: Psoriasis is a common chronic hyper proliferative skin disorder, with involvement of nail in about 25% patients. Onychomycosis is the fungal infection of the nail which also affects the psoriatic patients and thereby increasing disfigurement of nail in already clinically affected c...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Pvt. Ltd.
2019-04-01
|
| Series: | National Journal of Laboratory Medicine |
| Subjects: | |
| Online Access: | http://www.njlm.net/articles/PDF/2343/40175_CE[Ra1]_F(SHU)_PF1(AG_SHU)_PFA(SHU)_PB(AG_SHU)_PN(SHU).pdf |
| Summary: | Introduction: Psoriasis is a common chronic hyper proliferative
skin disorder, with involvement of nail in about 25% patients.
Onychomycosis is the fungal infection of the nail which
also affects the psoriatic patients and thereby increasing
disfigurement of nail in already clinically affected condition.
Aim: To know the prevalence of onychomycosis in psoriatic
patient with nail involvement. To determine the mycological
profile of onychomycosis in psoriasis patient and to perform the
antifungal susceptibility testing for the fungus isolated.
Materials and Methods: A cross-sectional study was done
for period of one year in a tertiary care center after obtaining
institutional ethical clearance. Nail scrapings were taken after
proper disinfection and subjected to KOH and cultured in
Sabouraud's dextrose agar and Dermatophyte test medium and
incubated upto four weeks. Tubes which were showing growth
were further processed for identification of species and antifungal
susceptibility test was done. Tubes which did not show growth at
the end of four weeks were reported as no growth.
Results: Total number of samples was 86. We had around
61.62% of males and rest were females. Most of our patients
were in the age group of 51 to 70 years. Four out of 86 samples
grew fungus of which two were Candida tropicalis and Fusarium
oxysporum and Alternaria alternata. There was no dermatophyte
isolated. We did not encountered any resistance.
Conclusion: It is better to screen for fungal infection of nails in
psoriatic patients with nail involvement. As the fungal infection
will cause more destruction and disfigurement, appropriate
antifungal therapy if started early will have better clinical
outcome. |
|---|---|
| ISSN: | 2277-8551 2455-6882 |