Harnessing the immunomodulatory effects of exercise to enhance the efficacy of monoclonal antibody therapies against B-cell haematological cancers: a narrative review

Harnessing the immunomodulatory effects of exercise to enhance the efficacy of monoclonal antibody therapies against B-cell haematological cancers: a narrative review

Therapeutic monoclonal antibodies (mAbs) are standard care for many B-cell haematological cancers. The modes of action for these mAbs include: induction of cancer cell lysis by activating Fcγ-receptors on innate immune cells; opsonising target cells for antibody-dependent cellular cytotoxicity or ph...

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Bibliographic Details
Main Authors: Harrison D. Collier-Bain, Frankie F. Brown, Adam J. Causer, Annabelle Emery, Rebecca Oliver, Sally Moore, James Murray, James E. Turner, John P. Campbell
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Oncology
Subjects:
exercise
cancer therapy
natural killer cells
phagocytes
complement proteins
T-cells
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1244090/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1244090/full

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