A Candidate Gene Cluster for the Bioactive Natural Product Gyrophoric Acid in Lichen-Forming Fungi

A Candidate Gene Cluster for the Bioactive Natural Product Gyrophoric Acid in Lichen-Forming Fungi

ABSTRACT Natural products of lichen-forming fungi are structurally diverse and have a variety of medicinal properties. Despite this, they have limited implementation in industry mostly because the corresponding genes are unknown for most of their natural products. Here, we implement a long-read sequ...

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Bibliographic Details
Main Authors: Garima Singh, Anjuli Calchera, Dominik Merges, Henrique Valim, Jürgen Otte, Imke Schmitt, Francesco Dal Grande
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:Microbiology Spectrum
Subjects:
biosynthetic genes
depsides
fungi
genome mining
long-read sequencing
microbial biotechnology
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00109-22

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