Analysis of trace element in intervertebral disc by Atomic Absorption Spectrometry techniques in degenerative disc disease in the Polish population
Objective. Although trace elements are regarded crucial and their content has been determined in number of tissue there are only few papers addressing this problem in intervertebral disc in humans. Most of the trace elements are important substrates of enzymes influencing metabolism and senescence p...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Institute of Rural Health
2015-05-01
|
| Series: | Annals of Agricultural and Environmental Medicine |
| Subjects: | |
| Online Access: | http://journals.indexcopernicus.com/fulltxt.php?ICID=1152096 |
| _version_ | 1819199227160428544 |
|---|---|
| author | Andrzej Nowakowski Łukasz Kubaszewski Marcin Frankowski Magdalena Wilk-Frańczuk Anetta Zioła-Frankowska Roża Czabak-Garbacz Jacek Kaczmarczyk Robert Gasik |
| author_facet | Andrzej Nowakowski Łukasz Kubaszewski Marcin Frankowski Magdalena Wilk-Frańczuk Anetta Zioła-Frankowska Roża Czabak-Garbacz Jacek Kaczmarczyk Robert Gasik |
| author_sort | Andrzej Nowakowski |
| collection | DOAJ |
| description | Objective. Although trace elements are regarded crucial and their content has been determined in number of tissue there are only few papers addressing this problem in intervertebral disc in humans. Most of the trace elements are important substrates of enzymes influencing metabolism and senescence process. Others are markers of environmental pollution. Therefore the aim of the research was to analyzed of the trace element content in the intervertebral disc, which may be a vital argument recognizing the background of degenerative changes to be the effect of the environment or metabolic factors.
Materials and methods. Material consist of 18 intervertebral disc from 15 patients, acquired in surgical procedure of due to the degenerative disease with Atomic Absorption Spectrometry content of Al, Cd, Co, Pb, Cu, Ni, Mo, Mg, Zn was evaluated.
Results. Only 4 of the trace elements were detected in all samples. The correlation analysis showed significant positive age correlation with Al and negative in case of Co. Among elements significant positive correlation was observed between Al/Pb, Co/Mo, Al/Mg, Al/Zn Pb/Zn and Mg/Zn. Negative correlation was observed in Al/Co, Cd/Mg, Co/Mg, Mo/Mg, Co/Zn and Mo/Zn.
Conclusions. This study is the first to our knowledge that profiles the elements in intervertebral disc in patients with degenerative changes. We have confirmed significant differences between the trace element contents in intervertebral disc and other tissue. It can be ground for further investigation. |
| first_indexed | 2024-12-23T03:12:59Z |
| format | Article |
| id | doaj.art-4fba465a640447af8989964ecc14e627 |
| institution | Directory Open Access Journal |
| issn | 1232-1966 1898-2263 |
| language | English |
| last_indexed | 2024-12-23T03:12:59Z |
| publishDate | 2015-05-01 |
| publisher | Institute of Rural Health |
| record_format | Article |
| series | Annals of Agricultural and Environmental Medicine |
| spelling | doaj.art-4fba465a640447af8989964ecc14e6272022-12-21T18:02:12ZengInstitute of Rural HealthAnnals of Agricultural and Environmental Medicine1232-19661898-22632015-05-0122878446362367Analysis of trace element in intervertebral disc by Atomic Absorption Spectrometry techniques in degenerative disc disease in the Polish populationAndrzej Nowakowski0Łukasz Kubaszewski1Marcin Frankowski2Magdalena Wilk-Frańczuk3Anetta Zioła-Frankowska4Roża Czabak-Garbacz5Jacek Kaczmarczyk6Robert Gasik7Department of Spine Surgery, Oncologic Orthopaedics and Traumatology, Poznan University of Medical Sciences, Poland Department of Orthopaedic and Traumatology, W. Dega University Hospital, University of Medical Sciences, Poznan, Poland; Clinic and Polyclinic of Neuroorthopedic and Neurology, Institute of Rheumatology, Warsaw, Poland Department of Water and Soil Analysis, Faculty of Chemistry, Adam Mickiewicz University in Poznan, Poland Andrzej Frycz Modrzewski Krakow University, Krakow, Poland Department of Water and Soil Analysis, Faculty of Chemistry, Adam Mickiewicz University in Poznan, Poland Health Resort Naleczow, Poland Department of Orthopaedic and Traumatology, W. Dega University Hospital, University of Medical Sciences, Poznan, Poland Clinic and Polyclinic of Neuroorthopedic and Neurology, Institute of Rheumatology, Warsaw, Poland Objective. Although trace elements are regarded crucial and their content has been determined in number of tissue there are only few papers addressing this problem in intervertebral disc in humans. Most of the trace elements are important substrates of enzymes influencing metabolism and senescence process. Others are markers of environmental pollution. Therefore the aim of the research was to analyzed of the trace element content in the intervertebral disc, which may be a vital argument recognizing the background of degenerative changes to be the effect of the environment or metabolic factors. Materials and methods. Material consist of 18 intervertebral disc from 15 patients, acquired in surgical procedure of due to the degenerative disease with Atomic Absorption Spectrometry content of Al, Cd, Co, Pb, Cu, Ni, Mo, Mg, Zn was evaluated. Results. Only 4 of the trace elements were detected in all samples. The correlation analysis showed significant positive age correlation with Al and negative in case of Co. Among elements significant positive correlation was observed between Al/Pb, Co/Mo, Al/Mg, Al/Zn Pb/Zn and Mg/Zn. Negative correlation was observed in Al/Co, Cd/Mg, Co/Mg, Mo/Mg, Co/Zn and Mo/Zn. Conclusions. This study is the first to our knowledge that profiles the elements in intervertebral disc in patients with degenerative changes. We have confirmed significant differences between the trace element contents in intervertebral disc and other tissue. It can be ground for further investigation.http://journals.indexcopernicus.com/fulltxt.php?ICID=1152096degeneration;pollution;Trace element;Environment |
| spellingShingle | Andrzej Nowakowski Łukasz Kubaszewski Marcin Frankowski Magdalena Wilk-Frańczuk Anetta Zioła-Frankowska Roża Czabak-Garbacz Jacek Kaczmarczyk Robert Gasik Analysis of trace element in intervertebral disc by Atomic Absorption Spectrometry techniques in degenerative disc disease in the Polish population Annals of Agricultural and Environmental Medicine degeneration;pollution;Trace element;Environment |
| title | Analysis of trace element in intervertebral disc by Atomic Absorption Spectrometry techniques in degenerative disc disease in the Polish population |
| title_full | Analysis of trace element in intervertebral disc by Atomic Absorption Spectrometry techniques in degenerative disc disease in the Polish population |
| title_fullStr | Analysis of trace element in intervertebral disc by Atomic Absorption Spectrometry techniques in degenerative disc disease in the Polish population |
| title_full_unstemmed | Analysis of trace element in intervertebral disc by Atomic Absorption Spectrometry techniques in degenerative disc disease in the Polish population |
| title_short | Analysis of trace element in intervertebral disc by Atomic Absorption Spectrometry techniques in degenerative disc disease in the Polish population |
| title_sort | analysis of trace element in intervertebral disc by atomic absorption spectrometry techniques in degenerative disc disease in the polish population |
| topic | degeneration;pollution;Trace element;Environment |
| url | http://journals.indexcopernicus.com/fulltxt.php?ICID=1152096 |
| work_keys_str_mv | AT andrzejnowakowski analysisoftraceelementinintervertebraldiscbyatomicabsorptionspectrometrytechniquesindegenerativediscdiseaseinthepolishpopulation AT łukaszkubaszewski analysisoftraceelementinintervertebraldiscbyatomicabsorptionspectrometrytechniquesindegenerativediscdiseaseinthepolishpopulation AT marcinfrankowski analysisoftraceelementinintervertebraldiscbyatomicabsorptionspectrometrytechniquesindegenerativediscdiseaseinthepolishpopulation AT magdalenawilkfranczuk analysisoftraceelementinintervertebraldiscbyatomicabsorptionspectrometrytechniquesindegenerativediscdiseaseinthepolishpopulation AT anettaziołafrankowska analysisoftraceelementinintervertebraldiscbyatomicabsorptionspectrometrytechniquesindegenerativediscdiseaseinthepolishpopulation AT rozaczabakgarbacz analysisoftraceelementinintervertebraldiscbyatomicabsorptionspectrometrytechniquesindegenerativediscdiseaseinthepolishpopulation AT jacekkaczmarczyk analysisoftraceelementinintervertebraldiscbyatomicabsorptionspectrometrytechniquesindegenerativediscdiseaseinthepolishpopulation AT robertgasik analysisoftraceelementinintervertebraldiscbyatomicabsorptionspectrometrytechniquesindegenerativediscdiseaseinthepolishpopulation |